Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.53 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.53 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.53 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138801 | 0.83 | ABCC9 (0.35) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6369348 | 0.83 | ABCC9 (0.62) | ABCC9ABCC8KCNJ11KCNJ8OPRD1 | |
| SCHEMBL9524977 | 0.82 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8OPRD1 | |
| SCHEMBL8123191 | 0.81 | ABCC9 (0.45) | ABCC9ABCC8KCNJ11KCNJ8OPRD1 | |
| SCHEMBL8133381 | 0.80 | ABCC9 (0.56) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8122964 | 0.80 | ABCC9 (0.37) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8311739 | 0.79 | ABCC9 (0.60) | ABCC9ABCC8KCNJ11KCNJ8OPRD1 | |
| SCHEMBL8130844 | 0.78 | ABCC9 (0.49) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL8123176 | 0.76 | GRM5 (0.39) | — | |
| SCHEMBL8315809 | 0.72 | ABCC9 (0.60) | ABCC9ABCC8KCNJ11KCNJ8OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655448-B1 | BENZOPYRAN AND BENZOXAZINE DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5977167-A | Benzopyran and benzoxazine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5874446-A | ANTIASTHMATICS, ANTIEPILEPSY AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-02-23 | — | — | US | disclosed |
| US-5614633-A | POTASSIUM CHANNEL ACTIVATOR | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0655448-A1 | BENZOPYRAN AND BENZOXAZINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-05-31 | — | — | EP | disclosed |