Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160548 | 0.83 | ALDH1A1 (0.51) | HSD17B10 | |
| SCHEMBL8130485 | 0.79 | KDM4E (0.42) | LDHAABCG2CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL10186707 | 0.76 | PTPN22 (0.48) | LDHAABCG2CYP1B1CYP1A1CYP1A2 | |
| SCHEMBL23111255 | 0.75 | GPR84 (0.41) | CYP1B1CYP1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6142391 | 0.74 | NCEH1 (0.51) | LDHANCEH1 | |
| SCHEMBL27374622 | 0.74 | AKR1C3 (0.44) | CYP2C9HSD17B10 | |
| SCHEMBL217075 | 0.73 | ESR1 (0.49) | CYP3A4POLBHSD17B10 | |
| SCHEMBL18889148 | 0.73 | PTPN22 (0.48) | LDHACYP1A2CYP2C9CYP2C19HSD17B10 | |
| SCHEMBL7761409 | 0.73 | LDHA (0.55) | LDHAABCG2CYP1B1NCEH1CYP1A1 | |
| SCHEMBL2808856 | 0.72 | PTPN7 (0.47) | CYP1B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6045968-A | COMPRISING AN ACID-DECOMPOSABLE NOVOLAK RESIN, AN ALKALI-SOLUBLE RESIN AND A PHOTO-ACID GENERATING AGENT; HIGH ALKALI SOLUBILITY, HIGH RESOLUTION, AND HIGH REPRODUCIBILITY | KABUSHIKI KAISHA TOSHIBA (JP) | 2000-04-04 | — | — | US | disclosed |
| US-5837419-A | ACID DECOMPOSABLE RESIN, PHOTO-ACID GENERATING AGENT AND NAPHTHOL NOVOLAK | KABUSHIKI KAISHA TOSHIBA (JP) | 1998-11-17 | — | — | US | disclosed |