Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL813136 | 0.94 | MCL1 (0.46) | MCL1MAPTCA1MT-CO2ALOX5 | |
| SCHEMBL811778 | 0.93 | MCL1 (0.45) | MCL1MAPTCA1MT-CO2ALOX5 | |
| SCHEMBL29079991 | 0.74 | POLB (0.40) | ALDH1A1TSHRPSEN1PSEN2APH1B | |
| SCHEMBL2455033 | 0.70 | GRM5 (0.39) | ALDH1A1ALOX15TSHR | |
| SCHEMBL813131 | 0.70 | DRD1 (0.35) | MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL14638749 | 0.67 | RIPK1 (0.35) | ALDH1A1ALOX15TSHRL3MBTL1LMNA | |
| SCHEMBL812452 | 0.67 | PSEN1 (0.30) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7254321 | 0.66 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1 | |
| SCHEMBL10606283 | 0.66 | — | — | |
| SCHEMBL361599 | 0.65 | DDB1 (0.48) | MCL1MAPTMT-CO2ALOX5ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968734-B2 | Organocatalysts and methods of use in chemical synthesis | STC.UNM (US) | 2011-06-28 | — | — | US | disclosed |
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | STC.UNM (US) | 2007-10-18 | — | — | US | disclosed |
| WO-2006007586-A1 | ORGANOCATALYSTS AND METHODS OF USE IN CHEMICAL SYNTHESIS | SCIENCE & TECHNOLOGY CORPORATION @ UNM (US) | 2006-01-19 | — | — | WO | disclosed |
| US-5250715-A | Optically active 2-methylenepentane derivative and process for preparing same | DAISO CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| US-5216187-A | Optically active 2-methylenepentane derivative and process for preparing same | DAISO CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5200538-A | Optically active 2-methylenecyclopentanone derivative and process for preparing same | DAISO CO., LTD. (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5180844-A | Optically active 2-methylenecyclopentanone derivative and process for preparing same | DAISO CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-5136066-A | Process for preparing optically active cyclopentenone derivative | DAISO CO., LTD. (JP) | 1992-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | SCO2, CBR1, CBR3 | MCL1 2420/4885MAPT 4442/4885CA1 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.