Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.55 |
| ▸ | AR | P10275 | 7/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 5/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690982 | 0.91 | PGR (0.57) | PGRARADORA3ADRA1ACHRM1 | |
| SCHEMBL7380 | 0.86 | PGR (0.59) | PGRARADORA3ADRA1ACHRM1 | |
| Fluocortolone SCHEMBL4644 | 0.85 | PGR (0.70) | PGRARADORA3ADRA1ACHRM1 | |
| Fluocortolone SCHEMBL21706397 | 0.85 | PGR (0.70) | PGRARADORA3ADRA1ACHRM1 | |
| Fluocortolone SCHEMBL11862489 | 0.85 | PGR (0.70) | PGRARADORA3ADRA1ACHRM1 | |
| Fluocortolone SCHEMBL11333890 | 0.85 | PGR (0.70) | PGRARADORA3ADRA1ACHRM1 | |
| Fluocortolone SCHEMBL13902941 | 0.85 | PGR (0.70) | PGRARADORA3ADRA1ACHRM1 | |
| Fluocortolone SCHEMBL19327147 | 0.85 | PGR (0.70) | PGRARADORA3ADRA1ACHRM1 | |
| Fluocortolone SCHEMBL3047399 | 0.85 | PGR (0.70) | PGRARADORA3ADRA1ACHRM1 | |
| Fluocortolone SCHEMBL11518086 | 0.85 | PGR (0.70) | PGRARADORA3ADRA1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2509 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-4301343-B1 | PHARMACEUTICAL COMPOSITIONS WITH REDUCED SIDE EFFECT AND METHODS OF USING THE SAME | TLC BIOPHARMACEUTICALS INC (US) | 2025-11-19 | — | — | EP | claimed |
| EP-4178579-B1 | 5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE AS GLUCOCORTICOID-SPARING AGENT | METRIOPHARM AG (CH) | 2025-02-12 | — | — | EP | claimed |
| EP-3773563-B1 | PRODRUGS OF FUSED-BICYCLIC C5AR ANTAGONISTS | CHEMOCENTRYX INC (US) | 2024-10-16 | — | — | EP | claimed |
| US-20240156839-A1 | PHARMACEUTICAL COMPOSITIONS WITH REDUCED SIDE EFFECT AND METHODS OF USING THE SAME | TLC BIOPHARMACEUTICALS, INC. | 2024-05-16 | — | — | US | claimed |
| EP-3728203-B1 | DIARYL SUBSTITUTED 6,5-FUSED RING COMPOUNDS AS C5aR INHIBITORS | CHEMOCENTRYX INC (US) | 2024-03-13 | — | — | EP | claimed |
| EP-4301343-A1 | PHARMACEUTICAL COMPOSITIONS WITH REDUCED SIDE EFFECT AND METHODS OF USING THE SAME | TLC Biopharmaceuticals, Inc. (US) | 2024-01-10 | — | — | EP | claimed |
| WO-2023183932-A2 | MONOBODIES BINDING TO INTERCELLULAR ADHESION MOLECULE 2 (ICAM-2) | NEW YORK UNIVERSITY (US) | 2023-09-28 | — | — | WO | claimed |
| US-20230241060-A1 | GLUCOCORTICOID-SPARING AGENT | METRIOPHARM AG (CH) | 2023-08-03 | — | — | US | claimed |
| EP-4214183-A1 | PHARMACEUTICAL COMPOSITIONS AND COMBINATIONS COMPRISING INHIBITORS OF THE ANDROGEN RECEPTOR AND USES THEREOF | Essa Pharma, Inc. (CA) | 2023-07-26 | — | — | EP | claimed |
| US-20030236298-A1 | 1,3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat VCAM-1 mediated disorders | ATHEROGENICS PHARMACEUTICALS, INC. | 2003-12-25 | — | — | US | claimed |
| CN-1447804-A | 1,3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat VCAM-1 mediated disorders | ATHEROGENICS INC (US) | 2003-10-08 | — | — | CN | claimed |
| US-6608101-B1 | Inflammatory disorders; 3-(2,4-dimethoxy-5-(thien-2-yl)phenyl)-1-(4-carboxymethoxy-3,5 -dimethoxyphenyl)-2-propen-1-one; | ATHEROGENICS, INC. | 2003-08-19 | — | — | US | claimed |
| EP-1330448-A2 | 1,3-BIS-(SUBSTITUTED-PHENYL)-2-PROPEN-1-ONES AND THEIR USE TO TREAT VCAM-1 MEDIATED DISORDERS | Atherogenics, Inc. (US) | 2003-07-30 | — | — | EP | claimed |
| WO-2003055464-A1 | MICRONIZED PHARMACEUTICAL OR NUTRACEUTICAL POWDER WITH IMMEDIATE RELEASE | BESINS INTERNATIONAL BELGIQUE (BE) | 2003-07-10 | — | — | WO | claimed |
| US-20030124191-A1 | Use of an immediate-release powder in pharmaceutical and nutraceutical compositions | GALENIX INNOVATIONS (FR) | 2003-07-03 | — | — | US | claimed |
| WO-2003043612-A1 | MICRONIZED FILM-FORMING POWDER COMPRISING AN ACTIVE SUBSTANCE | BESINS INTERNATIONAL BELGIQUE (BE) | 2003-05-30 | — | — | WO | claimed |
| US-20030096012-A1 | Film-forming powder, compositions containing it, methods for their preparation and their uses | GALENIX INNOVATIONS (FR) | 2003-05-22 | — | — | US | claimed |
| WO-2001098291-A2 | 1,3-BIS-(SUBSTITUTED-PHENYL)-2-PROPEN-1-ONES AND THEIR USE TO TREAT VCAM-1 MEDIATED DISORDERS | ATHEROGENICS, INC. (US) | 2001-12-27 | — | — | WO | claimed |
| WO-1997027862-A1 | SUPPLEMENTATION OF GLUCOCORTICOIDS | BELLARA MEDICAL PRODUCTS LIMITED (AU) | 1997-08-07 | — | — | WO | claimed |