Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | WDR5 | P61964 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ENGASE | Q8NFI3 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.34 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.34 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.34 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.34 |
| ▸ | ATP4A | P20648 | 2/20 | 0.34 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.34 |
| ▸ | ATP4B | P51164 | 2/20 | 0.34 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.34 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133110 | 0.82 | ATP4A (0.39) | MAPTWDR5KMT2AENGASENPC1 | |
| SCHEMBL2363618 | 0.78 | MAPT (0.54) | MAPTWDR5KMT2AENGASENPC1 | |
| SCHEMBL8141539 | 0.77 | CYP11B1 (0.39) | MAPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8059958 | 0.76 | NPC1 (0.61) | MAPTWDR5KMT2AENGASENPC1 | |
| SCHEMBL8071088 | 0.75 | NPC1 (0.39) | MAPTWDR5KMT2AENGASENPC1 | |
| SCHEMBL8128130 | 0.75 | SRPK1 (0.41) | ATP1A1ATP1B1ATP1A3ATP1B2ATP4A | |
| SCHEMBL4845769 | 0.68 | MAPT (0.31) | MAPTATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL8074080 | 0.67 | CYP2C9 (0.59) | MAPTWDR5KMT2AENGASECYP1A2 | |
| SCHEMBL8141545 | 0.67 | CYP11B1 (0.37) | MAPTWDR5CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8141541 | 0.67 | CYP19A1 (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19ATP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983263-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998054172-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-12-03 | — | — | WO | disclosed |