Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | CD38 | P28907 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141545 | 0.80 | CYP11B1 (0.37) | CYP11B1CYP11B2CYP19A1LMNACYP1A2 | |
| SCHEMBL8133102 | 0.77 | MAPT (0.34) | CYP11B1CYP11B2CYP19A1LMNACYP1A2 | |
| SCHEMBL8071180 | 0.73 | NOS2 (0.58) | CYP1A2CYP3A4CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL8069345 | 0.72 | CYP11B1 (0.38) | CYP11B1CYP11B2CYP19A1LMNACYP1A2 | |
| SCHEMBL8141541 | 0.71 | CYP19A1 (0.41) | CYP11B1CYP11B2CYP19A1LMNACYP1A2 | |
| SCHEMBL8074080 | 0.69 | CYP2C9 (0.59) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL8128130 | 0.67 | SRPK1 (0.41) | SRPK1OPRL1 | |
| SCHEMBL8133110 | 0.66 | ATP4A (0.39) | CYP11B1CYP11B2CYP19A1LMNACYP1A2 | |
| SCHEMBL8071082 | 0.66 | CYP19A1 (0.36) | CYP11B1CYP11B2CYP19A1LMNACYP1A2 | |
| SCHEMBL8071118 | 0.64 | NPC1 (0.47) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983263-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998054172-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-12-03 | — | — | WO | disclosed |