Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 4/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | CMA1 | P23946 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8147603 | 0.87 | PRSS1 (0.44) | CTSGCTRB1PRSS1CMA1TSHR | |
| SCHEMBL16414222 | 0.79 | CTRB1 (0.52) | CTSGCTRB1PRSS1CMA1TSHR | |
| SCHEMBL6049430 | 0.73 | KCNN4 (0.42) | TSHRKMT2AALDH1A1HTT | |
| SCHEMBL6823189 | 0.72 | TRPA1 (0.49) | CTSGCTRB1PRSS1CMA1KMT2A | |
| SCHEMBL6823591 | 0.72 | CYP24A1 (0.46) | CTSGCTRB1PRSS1CMA1POLB | |
| SCHEMBL7729984 | 0.71 | PRSS1 (0.42) | CTSGCTRB1PRSS1CMA1TSHR | |
| SCHEMBL8142294 | 0.70 | ADAM17 (0.31) | — | |
| SCHEMBL16691534 | 0.69 | CTRB1 (0.51) | CTRB1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL4192944 | 0.69 | CTRB1 (0.51) | CTRB1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6064974 | 0.69 | TSHR (0.45) | CTSGCTRB1PRSS1CMA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121475-A | Preparation of optically active β-hydroxyester derivatives and platinum-containing catalyst | UBE INDUSTRIES, LTD. (JP) | 2000-09-19 | — | — | US | disclosed |