Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | ILK | Q13418 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | NCS1 | P62166 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.35 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743922 | 0.84 | AHR (0.38) | DYRK1AILKALDH1A1MAPTHPGD | |
| SCHEMBL6475090 | 0.82 | SMN1; SMN2 (0.42) | ALOX5MEN1LMNAMAPTKMT2A | |
| SCHEMBL9439707 | 0.79 | SMN1; SMN2 (0.43) | MEN1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL19828320 | 0.79 | DYRK1A (0.41) | DYRK1AILKALOX5NCS1AKR1B1 | |
| SCHEMBL8127842 | 0.78 | RIPK1 (0.47) | DYRK1AALDH1A1LMNAPOLBMAPT | |
| SCHEMBL7956829 | 0.77 | DYRK1A (0.50) | DYRK1AILKALOX5NCS1AKR1B1 | |
| SCHEMBL9439557 | 0.75 | SMN1; SMN2 (0.40) | ALOX5SMN1; SMN2NPSR1TDP1PPARA | |
| SCHEMBL9743401 | 0.75 | PTPN1 (0.42) | DYRK1AILKMEN1ALDH1A1LMNA | |
| SCHEMBL21048412 | 0.74 | DYRK1A (0.45) | DYRK1AILKALOX5NCS1AKR1B1 | |
| SCHEMBL8128564 | 0.74 | ALOX5 (0.57) | DYRK1AILKALOX5NCS1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452076-B1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA CO (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5171746-A | THIAZOLE AND IMIDAZOLE DERIVATIVES AND ANTIULCER COMPOSITION CONTAINING SAME | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0452076-A1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-10-16 | — | — | EP | disclosed |