SCHEMBL813402

SCHEMBL813402

O=C(O)C(F)(F)CCC(F)(F)C(F)(F)CCC(F)(F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL814166 0.98 THRB (0.31) THRB
SCHEMBL4395002 0.81 THRB (0.44) THRB
SCHEMBL814625 0.80 THRB (0.42) THRBTET2
SCHEMBL7921925 0.79 THRB (0.48) THRB
Ammonia Solution, Strong SCHEMBL7929298 0.79 THRB (0.43) THRB
Ammonia Solution, Strong SCHEMBL814267 0.78 THRB (0.41) THRB
Ammonia Solution, Strong SCHEMBL7928038 0.78 THRB (0.46) THRB
SCHEMBL6746330 0.76 ACLY (0.32) THRB
SCHEMBL814270 0.73 ALDH1A1 (0.34)
SCHEMBL1358665 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8058375-B2 Use of ethylene-tetrafluoroethylene carboxylic acids and salts as surfactants for aqueous emulsion polymerization of fluorinated monomer E I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-15 US disclosed
EP-2370392-A1 ETHYLENE-TETRAFLUOROETHYLENE CARBOXYLIC ACIDS AND SALTS E. I. du Pont de Nemours and Company (US) 2011-10-05 EP disclosed
WO-2010075354-A1 ETHYLENE-TETRAFLUOROETHYLENE CARBOXYLIC ACIDS AND SALTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-01 WO disclosed
US-20100160550-A1 USE OF ETHYLENE-TETRAFLUOROETHYLENE CARBOXYLIC ACIDS AND SALTS AS SURFACTANTS FOR AQUEOUS EMULSION POLYMERIZATION OF FLUORINATED MONOMER E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-24 US disclosed
US-20100160584-A1 Ethylene-Tetrafluoroethylene Carboxylic Acids and Salts E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-24 US disclosed