SCHEMBL813451

SCHEMBL813451

COCC(CCc1ccccc1)(CCc1ccccc1)COC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TAAR1 Q96RJ0 3/20 0.39
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
CYP2A6 P11509 1/20 0.38
HTR2A P28223 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
SPHK2 Q9NRA0 2/20 0.37
SPHK1 Q9NYA1 1/20 0.37
IDO1 P14902 1/20 0.36
AOC3 Q16853 1/20 0.36
LTA4H P09960 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29174545 0.79 KCNH2 (0.36) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL813617 0.78 SLC6A2 (0.46) ALDH1A1TAAR1SMN1; SMN2IDO1LTA4H
SCHEMBL22666116 0.75 AKR1B10 (0.38) TDP1SMN1; SMN2
SCHEMBL17965759 0.75 SLC6A2 (0.39) ALDH1A1HPGDTAAR1SMN1; SMN2SPHK2
SCHEMBL6554382 0.74 ALDH1A1 (0.42) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL7277922 0.74 TP53 (0.44) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL11828432 0.73 MAOB (0.46) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL813495 0.72 SLC6A2 (0.50) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL19509051 0.72 ALDH1A1 (0.41) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL5077634 0.72 SLC6A2 (0.41) ALDH1A1TAAR1TDP1SMN1; SMN2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP claimed
US-11434315-B2 Propylene polymerizing solid catalyst for reducing VOC and method of producing polypropylene using same HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2022-09-06 US claimed
CN-119331130-B Solid catalyst component for olefin polymerization, olefin polymerization catalyst and application thereof 中国石油天然气股份有限公司 2026-05-15 CN disclosed
US-20260092131-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2026-04-02 US disclosed
EP-4594371-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2025-08-06 EP disclosed
US-20250188255-A1 POLYPROPYLENE-BASED RESIN COMPOSITION AND METHOD FOR PRODUCING SAME, FILM MOLDED ARTICLE, PACKAGE TO BE BROUGHT INTO CONTACT WITH FOOD, CONTAINER TO BE BROUGHT INTO CONTACT WITH FOOD, AND RETORT POUCH BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2025-06-12 US disclosed
US-20250154348-A1 POLYPROPYLENE RESIN COMPOSITION, SHEET MOLDED BODY, AND CONTAINER BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2025-05-15 US disclosed
US-12286504-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2025-04-29 US disclosed
WO-2025020304-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST AND USE OF CATALYST 中国石油天然气股份有限公司 2025-01-30 WO disclosed
CN-119331131-A Polymerization catalyst component of olefin, polymerization catalyst of olefin and application of polymerization catalyst component 中国石油天然气股份有限公司 2025-01-21 CN disclosed
CN-119331135-A Olefin polymerization catalyst component, olefin polymerization catalyst and application thereof 中国石油天然气股份有限公司 2025-01-21 CN disclosed
EP-0728770-A1 Process for the preparation of solid catalyst components for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1996-08-28 EP disclosed
EP-0728769-A1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1996-08-28 EP disclosed
EP-0434082-B1 Components and catalysts for the polymerization of olefins HIMONT INC (US) 1995-10-25 EP disclosed
EP-0362705-B1 Catalysts for the polymerization of olefins HIMONT INC (US) 1995-01-11 EP disclosed
US-5122492-A Magnesium dihalide, titanium halide or halogen alcoholate on porous metal oxide HIMONT INCORPORATED (US) 1992-06-16 US disclosed
CN-1052681-A The catalyst component of olefinic polymerization and catalyzer HIMONT INC (US) 1991-07-03 CN disclosed
EP-0434082-A2 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1991-06-26 EP disclosed
US-4978648-A Alkyl-aluminum, diether, magnesium dichloride, titanium halide components; propylene polymerization HIMONT INCORPORATED (US) 1990-12-18 US disclosed
EP-0362705-A2 Catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1990-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092131-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS ZDHHC7, DNER, MDM4 ALDH1A1 881/4885HPGD 747/4885ALOX15 971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.