Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 18/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014760 | 0.67 | KDM5B (0.50) | KDM5BTP53 | |
| SCHEMBL7131027 | 0.67 | KDM5B (0.50) | KDM5BKDM4E | |
| SCHEMBL7665757 | 0.64 | KDM5B (0.44) | KDM5B | |
| SCHEMBL17784391 | 0.60 | KDM5B (0.43) | KDM5B | |
| SCHEMBL6403829 | 0.57 | BACE1 (0.49) | KDM4E | |
| SCHEMBL25575726 | 0.56 | CDK9 (0.41) | — | |
| SCHEMBL25212201 | 0.55 | NOS3 (0.35) | — | |
| SCHEMBL24879507 | 0.55 | SCN5A (0.40) | — | |
| SCHEMBL7664337 | 0.54 | KDM5B (0.39) | KDM5B | |
| SCHEMBL11463496 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0978517-A2 | Triazolopurines, process for their preparation and their use as medicaments | Boehringer Ingelheim Pharma KG (DE) | 2000-02-09 | — | — | EP | disclosed |
| EP-0880524-A1 | NEW TRIAZOLOPURINES, METHOD OF PREPARING THEM AND THEIR USE AS DRUGS | Boehringer Ingelheim Pharma KG (DE) | 1998-12-02 | — | — | EP | disclosed |
| WO-1998003511-A1 | NEW TRIAZOLOPURINES, METHOD OF PREPARING THEM AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-01-29 | — | — | WO | disclosed |