Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19730669 | 0.81 | ALDH1A1 (0.46) | TRPA1TTRALDH1A1NPSR1CYP1A2 | |
| SCHEMBL27811445 | 0.79 | ALDH1A1 (0.43) | TRPA1ATMTTRALDH1A1CYP1A2 | |
| SCHEMBL7525298 | 0.79 | TYR (0.39) | TRPA1ATMTTRALDH1A1TDP1 | |
| SCHEMBL15485256 | 0.77 | ALDH1A1 (0.53) | TRPA1ATMALDH1A1POLBRECQL | |
| SCHEMBL23915 | 0.77 | ALDH1A1 (0.53) | TRPA1ATMALDH1A1POLBRECQL | |
| SCHEMBL29407125 | 0.77 | ALDH1A1 (0.53) | TRPA1ATMALDH1A1POLBRECQL | |
| SCHEMBL8527219 | 0.75 | CYP1A2 (0.35) | TRPA1ATMPOLBCYP1A2TSHR | |
| SCHEMBL12302293 | 0.73 | TTR (0.44) | TTRALDH1A1RECQLTDP1KDM4E | |
| SCHEMBL6858668 | 0.72 | CYP1A2 (0.33) | TRPA1ATMPOLBCYP1A2TSHR | |
| SCHEMBL339799 | 0.72 | TDP2 (0.44) | TRPA1ATMALDH1A1POLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000108-B2 | Process for selectively polymerizing ethylene and catalyst therefor | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-04-07 | — | — | US | disclosed |
| US-20140163186-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-06-12 | — | — | US | disclosed |
| US-8609794-B2 | Process for selectively polymerizing ethylene and catalyst therefor | DOW GLOBAL TECHNOLOGIES, LLC. (US) | 2013-12-17 | — | — | US | disclosed |
| EP-2491062-B1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-11 | — | — | EP | disclosed |
| CN-102906129-A | Process for selectively polymerizing ethylene and catalyst therefor | DOW GLOBAL TECHNOLOGIES LLC | 2013-01-30 | — | — | CN | disclosed |
| EP-2491062-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | Dow Global Technologies LLC (US) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011146291-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | WEE2, NOTUM, WEE1 | TRPA1 2847/4885ATM 3948/4885TTR 4757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.