SCHEMBL339799

SCHEMBL339799

Cc1ccc(-c2ccc(C)c(C)c2O)c(O)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 1/20 0.44
NSD2 O96028 1/20 0.44
HSP90AA1 P07900 1/20 0.44
PAX8 Q06710 1/20 0.44
POLB P06746 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
RECQL P46063 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TRPA1 O75762 2/20 0.42
ATM Q13315 1/20 0.42
ALDH1A1 P00352 2/20 0.41
ELANE P08246 2/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
MAPT P10636 3/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPK1 P28482 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16236725 0.84 TRPA1 (0.46) POLBNPSR1RECQLTDP1TRPA1
SCHEMBL13030469 0.83 MAPT (0.38) TDP2NSD2HSP90AA1PAX8POLB
SCHEMBL29407125 0.81 ALDH1A1 (0.53) TDP2NSD2HSP90AA1PAX8POLB
SCHEMBL23915 0.81 ALDH1A1 (0.53) TDP2NSD2HSP90AA1PAX8POLB
SCHEMBL15485256 0.81 ALDH1A1 (0.53) TDP2NSD2HSP90AA1PAX8POLB
SCHEMBL8067080 0.81 TDP2 (0.40) TDP2NSD2HSP90AA1PAX8POLB
SCHEMBL6423564 0.81 ESR2 (0.53) TDP2NSD2HSP90AA1PAX8POLB
SCHEMBL5590802 0.79 MCL1 (0.42) TDP2NSD2HSP90AA1PAX8POLB
SCHEMBL21861870 0.79 ALDH1A1 (0.50) TDP2NSD2HSP90AA1PAX8POLB
SCHEMBL11747820 0.78 TRPA1 (0.39) TDP2NSD2HSP90AA1PAX8POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4175331-A None JP disclosed
US-9795952-B2 Bidentate ligands for hydroformylation of ethylene DOW TECHNOLOGY INVESTMENTS LLC (US) 2017-10-24 US disclosed
US-20150328628-A1 Bidentate Ligands for Hydroformylation of Ethylene THE DOW CHEMICAL COMPANY 2015-11-19 US disclosed
WO-2014088800-A1 BIDENTATE LIGANDS FOR HYDROFORMYLATION OF ETHYLENE DOW TECHNOLOGY INVESTMENTS LLC (US) 2014-06-12 WO disclosed
EP-2740535-A1 Bidentate ligands for hydroformylation of ethylene Dow Technology Investments LLC (US) 2014-06-11 EP disclosed
EP-2271651-B1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-01-01 EP disclosed
EP-2346887-B1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES DOW TECHNOLOGY INVESTMENTS LLC (US) 2013-12-25 EP disclosed
US-8546600-B2 Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite DOW TECHNOLOGY INVESTMENTS LLC 2013-10-01 US disclosed
EP-2257560-B1 SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS UNION CARBIDE CHEM PLASTIC (US) 2013-07-17 EP disclosed
US-8471066-B2 Slurry process for phosphoromonochloridite synthesis UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC 2013-06-25 US disclosed
EP-2271651-A1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS Dow Global Technologies Inc. (US) 2011-01-12 EP disclosed
EP-2257560-A1 SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS Union Carbide Chemicals & Plastics Technology Llc (Formerly Union Carbide Chemicals & Plastics Technology Corporation) (US) 2010-12-08 EP disclosed
WO-2010042313-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES DOW TECHNOLOGY INVESTMENTS LLC (US) 2010-04-15 WO disclosed
US-20090247790-A1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS UNION CARBIDE CORPORATION 2009-10-01 US disclosed
WO-2009120210-A1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS DOW GLOBAL TECHNOLOGIES INC. (US) 2009-10-01 WO disclosed
WO-2009120529-A1 SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (FORMERLY UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION) (US) 2009-10-01 WO disclosed
JP-2007177180-A EPOXY RESIN VARNISH, PHOTOSENSITIVE RESIN COMPOSITION AND ITS CURED PRODUCT NIPPON KAYAKU CO LTD 2007-07-12 JP disclosed
US-6255409-B1 EPOXY RESIN COMPOSITION COMPRISING BIFUNCTIONAL CRYSTALLINE EPOXY COMPOUND, AMORPHOUS TRISPHENOLMETHANE TYPE EPOXY COMPOUND HAVING THREE OR MORE EPOXY GROUPS IN MOLECULE, AND EPOXY CURING AGENT HAVING PHENOLIC HYDROXYL GROUPS SUMITOMO CHEMICAL CO., LTD. (JP) 2001-07-03 US disclosed
EP-0943639-A2 Epoxy resin composition and resin-encapsulated semiconductor device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-22 EP disclosed
JP-H04175331-A POWDERY EPOXY RESIN COMPOSITION YUKA SHELL EPOXY KK 1992-06-23 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247790-A1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS PIM3, PLCB3, PLCD1 TDP2 3987/4885NSD2 3749/4885HSP90AA1 4430/4885
US-20150328628-A1 Bidentate Ligands for Hydroformylation of Ethylene HRH4, HRH3, H1-4 TDP2 4245/4885NSD2 4184/4885HSP90AA1 4073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.