SCHEMBL8136181

SCHEMBL8136181

O=S(=O)(OC(F)(F)CF)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
PARL Q9H300 1/20 0.38
PSIP1 O75475 1/20 0.38
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
KMT2A Q03164 1/20 0.37
APOBEC3G Q9HC16 1/20 0.36
PPARG P37231 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA5A P35218 2/20 0.35
CA9 Q16790 2/20 0.35
HSD17B10 Q99714 1/20 0.35
CA12 O43570 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1414702 0.81 GAA (0.42) ALDH1A1KMT2ACA1CA2CA5A
SCHEMBL1515703 0.79 HTR6 (0.44) HTR6TDP1PARLPSIP1ALDH1A1
SCHEMBL4135164 0.79 PSIP1 (0.41) HTR6TDP1PARLPSIP1ALDH1A1
SCHEMBL28361716 0.78 HTR6 (0.42) HTR6TDP1PARLPSIP1ALDH1A1
SCHEMBL31304753 0.78 HTR6 (0.42) HTR6TDP1PARLPSIP1ALDH1A1
SCHEMBL4127173 0.76 HTR6 (0.41) HTR6TDP1PARLPSIP1ALDH1A1
SCHEMBL28378674 0.76 HTR6 (0.41) HTR6TDP1PARLPSIP1ALDH1A1
SCHEMBL4132885 0.76 HTR6 (0.41) HTR6TDP1PARLPSIP1ALDH1A1
SCHEMBL7093808 0.75 ALDH1A1 (0.34) HTR6TDP1PARLPSIP1ALDH1A1
SCHEMBL4127254 0.73 HTR6 (0.38) HTR6TDP1PARLALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010767-A Haloalkyl bisamide compound and application thereof 山东熙霖生物科技有限公司 2026-05-12 CN disclosed
US-6046367-A Triphenylbis (fluoroalkoxy) phosphoranes and fluorinated ketals E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-04-04 US disclosed
US-5623089-A Triphenylbis(fluoroalkoxy) phosphoranes and fluorinated ketals E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-04-22 US disclosed
EP-0688326-A1 TRIPHENYLBIS (FLUOROALKOXY) PHOSPHORANES AND FLUORINATED KETALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-12-27 EP disclosed
WO-1994020509-A1 TRIPHENYLBIS (FLUOROALKOXY) PHOSPHORANES AND FLUORINATED KETALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-09-15 WO disclosed