Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809532 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTHSP90AA1MAPK1AGTR1 | |
| SCHEMBL809493 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTHSP90AA1MAPK1AGTR1 | |
| SCHEMBL1319211 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MAPTHSP90AA1MAPK1AGTR1 | |
| SCHEMBL27165026 | 0.86 | ALDH1A1 (0.37) | ALDH1A1MAPTTDP1HPGDSMN1; SMN2 | |
| SCHEMBL27204537 | 0.86 | ALDH1A1 (0.37) | ALDH1A1MAPTTDP1HPGDSMN1; SMN2 | |
| SCHEMBL1319209 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MAPTHSP90AA1MAPK1AGTR1 | |
| SCHEMBL27165050 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MAPTMAPK1HPGDSMN1; SMN2 | |
| SCHEMBL27165030 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MAPTHSP90AA1MAPK1AGTR1 | |
| SCHEMBL27165110 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MAPTMAPK1HPGDSMN1; SMN2 | |
| SCHEMBL809461 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTMAPK1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240076263-A1 | METHOD FOR PREPARING CHIRAL NITRO DERIVATIVES USING ORGANIC CHIRAL CATALYST COMPOUNDS AND ECO-FRIENDLY SOLVENTS | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, (KR) | 2024-03-07 | — | — | US | disclosed |
| US-7968734-B2 | Organocatalysts and methods of use in chemical synthesis | STC.UNM (US) | 2011-06-28 | — | — | US | disclosed |
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | STC.UNM (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | SCO2, CBR1, CBR3 | ALDH1A1 1287/4885MAPT 4442/4885HSP90AA1 4561/4885 |
| US-20240076263-A1 | METHOD FOR PREPARING CHIRAL NITRO DERIVATIVES USING ORGANIC CHIRAL CATALYST COMPOUNDS AND ECO-FRIENDLY SOLVENTS | PNMT, TNNC1, IDO1 | ALDH1A1 2401/4885MAPT 3216/4885HSP90AA1 4579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.