Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.32 |
| ▸ | CDK1 | P06493 | 4/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.32 |
| ▸ | GSK3A | P49840 | 4/20 | 0.32 |
| ▸ | GSK3B | P49841 | 4/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
| ▸ | AKT2 | P31751 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143723 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL16693033 | 0.73 | SMN1; SMN2 (0.40) | SMN1; SMN2CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL10611243 | 0.71 | METAP2 (0.44) | METAP2METAP1EGLN1CCNB2CDK1 | |
| SCHEMBL29433971 | 0.71 | METAP2 (0.44) | METAP2METAP1EGLN1 | |
| SCHEMBL4719448 | 0.71 | METAP2 (0.44) | METAP2METAP1EGLN1 | |
| SCHEMBL976118 | 0.71 | METAP2 (0.48) | METAP2METAP1EGLN1CCNB2CDK1 | |
| SCHEMBL6012369 | 0.71 | METAP2 (0.44) | METAP2METAP1EGLN1CCNB2CDK1 | |
| Zarzissine SCHEMBL1514280 | 0.71 | NUDT1 (0.50) | METAP2METAP1SMN1; SMN2EGLN1CDK5 | |
| SCHEMBL14409054 | 0.71 | METAP2 (0.44) | METAP2METAP1EGLN1 | |
| SCHEMBL30615128 | 0.71 | METAP2 (0.44) | METAP2METAP1EGLN1CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580638-B | Modified biochar/carbon fiber/PEEK composite material and preparation method thereof | 江苏君华特种高分子材料股份有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-118580638-A | Modified biochar/carbon fiber/PEEK composite material and preparation method thereof | 江苏君华特种高分子材料股份有限公司 | 2024-09-03 | — | — | CN | claimed |
| CN-118580638-B | Modified biochar/carbon fiber/PEEK composite material and preparation method thereof | 江苏君华特种高分子材料股份有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-118580638-A | Modified biochar/carbon fiber/PEEK composite material and preparation method thereof | 江苏君华特种高分子材料股份有限公司 | 2024-09-03 | — | — | CN | disclosed |
| EP-4219465-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3498701-B1 | PRMT5 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2023-02-22 | — | — | EP | disclosed |
| EP-3362100-B1 | HINDERED DISULFIDE DRUG CONJUGATES | GENENTECH INC (US) | 2022-06-22 | — | — | EP | disclosed |
| CN-113430521-A | Environment-friendly acidic etching additive suitable for thin line manufacturing and application thereof | 深圳市板明科技股份有限公司 | 2021-09-24 | — | — | CN | disclosed |
| WO-2021143246-A1 | ORGANIC ELECTROLUMINESCENT DEVICE AND FUSED RING-BASED AROMATIC AMINE COMPOUNDS | 广州华睿光电材料有限公司 | 2021-07-22 | — | — | WO | disclosed |
| EP-2935247-B1 | PRMT5 INHIBITORS AND USES THEREOF | EPIZYME INC (US) | 2019-08-28 | — | — | EP | disclosed |
| EP-3498701-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2019-06-19 | — | — | EP | disclosed |
| US-20070203209-A1 | Useful indole compounds | IRONWOOD PHARMACEUTICALS, INC. | 2007-08-30 | — | — | US | disclosed |
| US-7229943-B2 | Polymerisation and oligomerisation catalysts | INNOVENE EUROPE LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| US-7229943-B2 | Polymerisation and oligomerisation catalysts | INNOVENE EUROPE LIMITED (GB) | 2007-06-12 | — | — | US | disclosed |
| US-7220757-B2 | Compositions and methods for topical administration of 2-NH-heteroarylimidazoles | REPLIDYNE, INC. (US) | 2007-05-22 | — | — | US | disclosed |
| US-7220757-B2 | Compositions and methods for topical administration of 2-NH-heteroarylimidazoles | REPLIDYNE, INC. (US) | 2007-05-22 | — | — | US | disclosed |
| WO-2007022501-A2 | USEFUL INDOLE COMPOUNDS | MICROBIA, INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007015074-A1 | DIENE POLYMERISATION | INEOS EUROPE LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |
| US-4007170-A | SILVER HALIDE SENSITIZERS | EASTMAN KODAK COMPANY (US) | 1977-02-08 | — | — | US | disclosed |
| US-3936308-A | Photographic emulsions containing methine dyes having a 1H-imidazo[4,5-b]pyrazine nucleus | EASTMAN KODAK COMPANY (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203209-A1 | Useful indole compounds | TPH2, HRH2, HRH1 | METAP2 427/4885METAP1 1049/4885SMN1; SMN2 2272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.