Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16226110 | 0.85 | CHRNA7 (0.52) | HTR1ACHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5746025 | 0.82 | PRCP (0.38) | HTR1ACHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL10349654 | 0.78 | HTR1A (0.55) | HTR1ACHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8517882 | 0.77 | ATM (0.48) | HTR1ACHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8660338 | 0.77 | ATM (0.48) | HTR1ACHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30561555 | 0.77 | ATM (0.48) | HTR1ACHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27979491 | 0.77 | ATM (0.48) | HTR1ACHRNA7CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL10384152 | 0.76 | HTR1A (0.53) | HTR1ACHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL16226760 | 0.74 | ATM (0.44) | HTR1ACHRNA7CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL16226051 | 0.74 | ATM (0.44) | HTR1ACHRNA7CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067610-B2 | Synthesis of terminal alkenes from internal alkenes and ethylene via olefin metathesis | MATERIA, INC. | 2011-11-29 | — | — | US | disclosed |
| US-20080027194-A1 | Synthesis of terminal alkenes from internal alkenes and ethylene via olefin metathesis | MATERIA, INC. | 2008-01-31 | — | — | US | disclosed |