SCHEMBL8517882

SCHEMBL8517882

CC1C(c2ccccc2)N1C

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ATM Q13315 4/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.48
CHRNA7 P36544 2/20 0.44
NPSR1 Q6W5P4 3/20 0.44
HTR1A P08908 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HTT P42858 2/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.41
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
ABCB1 P08183 1/20 0.37
RIPK1 Q13546 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30561555 1.00 ATM (0.48) ATMMEN1KMT2AALDH1A1TSHR
SCHEMBL8660338 1.00 ATM (0.48) ATMMEN1KMT2AALDH1A1TSHR
SCHEMBL16001322 0.82 ATM (0.47) ATMMEN1KMT2AALDH1A1TSHR
SCHEMBL22901480 0.82 ATM (0.47) ATMMEN1KMT2AALDH1A1TSHR
SCHEMBL11628193 0.77 ATM (0.43) ATMMEN1KMT2AALDH1A1TSHR
SCHEMBL813719 0.77 HTR1A (0.47) ATMMEN1KMT2AALDH1A1TSHR
SCHEMBL14223522 0.77 ALDH1A1 (0.43) ATMMEN1KMT2AALDH1A1TSHR
Iodide SCHEMBL11744749 0.75 ATM (0.42) ATMMEN1KMT2AALDH1A1TSHR
SCHEMBL12292028 0.75 CHRNA7 (0.42) ATMMEN1KMT2AALDH1A1TSHR
SCHEMBL10349654 0.75 HTR1A (0.55) ATMMEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213502-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms Pharmapotheca A, Inc. 2025-07-03 US disclosed
US-12208068-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms Pharmapotheca A Inc. (US) 2025-01-28 US disclosed
CN-117603115-A Method for preparing cyclic amine from amino alcohol 中海油天津化工研究设计院有限公司 2024-02-27 CN disclosed
US-20230321010-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms CHEMAPOTHECA, LLC (US) 2023-10-12 US disclosed
US-11717498-B2 Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms Pharmapotheca A, Inc. (US) 2023-08-08 US disclosed
US-11123310-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms PHARMAPOTHECA, LLC (US) 2021-09-21 US disclosed
US-20210030699-A1 Methods of Treatment Using Amphetamine Controlled Release, Prodrug, and Abuse Deterrent Dosage Forms PHARMAPOTHECA, LLC (US) 2021-02-04 US disclosed
US-20200352883-A1 METHODS OF TREATMENT USING AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS CHEMAPOTHECA, LLC (US) 2020-11-12 US disclosed
EP-3478363-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE DETERRENT DOSAGE FORMS Chemapotheca LLC (US) 2019-05-08 EP disclosed
US-20180243241-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS CHEMAPOTHECA, LLC 2018-08-30 US disclosed
US-9988349-B2 Direct stereospecific synthesis of unprotected aziridines from olefins NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2018-06-05 US disclosed
US-9988349-B2 Direct stereospecific synthesis of unprotected aziridines from olefins NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2018-06-05 US disclosed
WO-2017147375-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE DETERRENT DOSAGE FORMS CHEMAPOTHECA, LLC (US) 2017-08-31 WO disclosed
US-20160340305-A1 DIRECT STEREOSPECIFIC SYNTHESIS OF UNPROTECTED AZIRIDINES FROM OLEFINS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-11-24 US disclosed
US-20160340305-A1 DIRECT STEREOSPECIFIC SYNTHESIS OF UNPROTECTED AZIRIDINES FROM OLEFINS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-11-24 US disclosed
EP-0871621-A4 ASYMMETRIC SYNTHESIS CATALYZED BY TRANSITION METAL COMPLEXES WITH NEW CHIRAL LIGANDS PENN STATE RES FOUND (US) 1999-10-13 EP disclosed
EP-0871621-A1 ASYMMETRIC SYNTHESIS CATALYZED BY TRANSITION METAL COMPLEXES WITH NEW CHIRAL LIGANDS THE PENN STATE RESEARCH FOUNDATION (US) 1998-10-21 EP disclosed
WO-1997013763-A1 ASYMMETRIC SYNTHESIS CATALYZED BY TRANSITION METAL COMPLEXES WITH NEW CHIRAL LIGANDS THE PENN STATE RESEARCH FOUNDATION (US) 1997-04-17 WO disclosed
US-4173580-A Production of β-haloalkylaminosulfonyl halides BASF AKTIENGESELLSCHAFT (DE) 1979-11-06 US disclosed
US-4014931-A FROM AZIRIDINE AND SULFURYL HALIDE BASF AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11123310-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms SLC6A3, CES2, SLC6A2 ATM 3889/4885MEN1 1784/4885KMT2A 1605/4885
US-11717498-B2 Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms SLC6A3, SLC6A2, CES2 ATM 4009/4885MEN1 2092/4885KMT2A 1539/4885
US-20160340305-A1 DIRECT STEREOSPECIFIC SYNTHESIS OF UNPROTECTED AZIRIDINES FROM OLEFINS AAAS, NISCH, HNMT ATM 2082/4885MEN1 1388/4885KMT2A 808/4885
US-20200352883-A1 METHODS OF TREATMENT USING AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS SLC6A3, SLC6A2, CES2 ATM 4098/4885MEN1 1941/4885KMT2A 1492/4885
US-20230321010-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms SLC6A3, CES2, SLC6A2 ATM 3782/4885MEN1 1840/4885KMT2A 1784/4885
US-20210030699-A1 Methods of Treatment Using Amphetamine Controlled Release, Prodrug, and Abuse Deterrent Dosage Forms SLC6A3, SLC6A2, CES2 ATM 4009/4885MEN1 2092/4885KMT2A 1539/4885
US-12208068-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms SLC6A3, CES2, SLC6A2 ATM 3782/4885MEN1 1840/4885KMT2A 1784/4885
US-20250213502-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms SLC6A3, CES2, SLC6A2 ATM 3889/4885MEN1 1784/4885KMT2A 1605/4885
US-20180243241-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS SLC6A3, CES2, SLC6A2 ATM 3889/4885MEN1 1784/4885KMT2A 1605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.