Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30561555 | 1.00 | ATM (0.48) | ATMMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8517882 | 1.00 | ATM (0.48) | ATMMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL16001322 | 0.82 | ATM (0.47) | ATMMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL22901480 | 0.82 | ATM (0.47) | ATMMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL11628193 | 0.77 | ATM (0.43) | ATMMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL813719 | 0.77 | HTR1A (0.47) | ATMMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL14223522 | 0.77 | ALDH1A1 (0.43) | ATMMEN1KMT2AALDH1A1TSHR | |
| Iodide SCHEMBL11744749 | 0.75 | ATM (0.42) | ATMMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL12292028 | 0.75 | CHRNA7 (0.42) | ATMMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL10349654 | 0.75 | HTR1A (0.55) | ATMMEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767276-A | Asymmetric synthesis catalyzed by transition metal complexes with new chiral ligands | THE PENN STATE RESEARCH FOUNDATION (US) | 1998-06-16 | — | — | US | disclosed |