Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6632184 | 0.81 | MAPT (0.33) | MAPTGAAALDH1A1HSPA1APTPN7 | |
| SCHEMBL6628775 | 0.71 | SIRT1 (0.32) | MAPTGAAALDH1A1KDM4E | |
| SCHEMBL11498471 | 0.71 | — | — | |
| SCHEMBL385982 | 0.70 | MAPT (0.40) | MAPTGAAALDH1A1HSPA1APTPN7 | |
| SCHEMBL11205813 | 0.70 | GAA (0.40) | MAPTGAAALDH1A1P2RX4MEN1 | |
| Hydrochloric Acid SCHEMBL7435031 | 0.69 | MAPT (0.39) | MAPTGAAALDH1A1HSPA1APTPN7 | |
| SCHEMBL5800011 | 0.68 | ALDH1A1 (0.57) | MAPTGAAALDH1A1HSPA1APTPN7 | |
| SCHEMBL3749720 | 0.68 | ALDH1A1 (0.57) | MAPTGAAALDH1A1HSPA1APTPN7 | |
| Hydrochloric Acid SCHEMBL28797396 | 0.67 | ALDH1A1 (0.56) | MAPTGAAALDH1A1HSPA1APTPN7 | |
| Hydrochloric Acid SCHEMBL28270652 | 0.67 | ALDH1A1 (0.56) | MAPTGAAALDH1A1HSPA1APTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1649847-A | Method for producing optically active sulfoxide derivative | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-08-03 | — | — | CN | disclosed |
| EP-1039899-A2 | PHARMACEUTICAL COMPOSITION FOR ANTAGONIZING CCR5 COMPRISING ANILIDE DERIVATIVE | Takeda Chemical Industries, Ltd. (JP) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999032100-A2 | PHARMACEUTICAL COMPOSITION FOR ANTAGONIZING CCR5 COMPRISING ANILIDE DERIVATIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-01 | — | — | WO | disclosed |