Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | DHX9 | Q08211 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671663 | 0.90 | OPRD1 (0.75) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL8124466 | 0.85 | OPRD1 (0.67) | OPRM1OPRD1OPRK1KCNH2HDAC6 | |
| SCHEMBL8134558 | 0.84 | OPRD1 (0.81) | OPRM1OPRD1OPRK1 | |
| SCHEMBL8135859 | 0.84 | OPRD1 (0.65) | OPRM1OPRD1OPRK1HDAC6 | |
| SCHEMBL8133582 | 0.84 | OPRD1 (0.65) | OPRM1OPRD1OPRK1HDAC6 | |
| Diethylamine SCHEMBL7672966 | 0.82 | OPRD1 (0.75) | OPRM1OPRD1OPRK1HDAC6 | |
| SCHEMBL7673845 | 0.80 | OPRD1 (0.87) | OPRM1OPRD1OPRK1HDAC6 | |
| SCHEMBL8132760 | 0.78 | OPRD1 (0.58) | OPRM1OPRD1OPRK1HDAC6 | |
| SCHEMBL7668256 | 0.77 | OPRD1 (0.63) | OPRM1OPRD1OPRK1HDAC6 | |
| SCHEMBL7665748 | 0.76 | OPRD1 (0.82) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038872-A1 | 4-Phenyl-4-heteroarylpiperdine derivatives as opioid receptor ligands | Pfizer Products Inc. (US) | 2000-09-27 | — | — | EP | disclosed |