SCHEMBL792984

SCHEMBL792984

O=[N+]([O-])C=Cc1cc(Br)cs1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 12/20 0.41
VCP P55072 4/20 0.41
LMNA P02545 1/20 0.38
EGFR P00533 2/20 0.37
ABL1 P00519 1/20 0.37
ABL2 P42684 1/20 0.37
HSP90AA1 P07900 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL792983 1.00 FBP1 (0.41) FBP1VCPLMNAEGFRABL1
SCHEMBL11034872 0.81 FBP1 (0.50) FBP1VCPLMNAEGFRABL1
SCHEMBL1866963 0.79 FBP1 (0.47) FBP1VCPLMNAEGFRABL1
SCHEMBL1866964 0.79 FBP1 (0.47) FBP1VCPLMNAEGFRABL1
SCHEMBL17713675 0.79 FBP1 (0.47) FBP1VCPLMNAEGFRABL1
SCHEMBL1363279 0.79 FBP1 (0.47) FBP1VCPEGFRABL1ABL2
SCHEMBL1363276 0.79 FBP1 (0.47) FBP1VCPEGFRABL1ABL2
SCHEMBL2491537 0.76 NPC1 (0.40) LMNA
SCHEMBL2491542 0.76 NPC1 (0.40) LMNA
SCHEMBL8138642 0.72 FBP1 (0.48) FBP1VCPLMNAEGFRABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2982368-A1 Small molecule compounds displacing focal adhesion core components Universität Konstanz (DE) 2016-02-10 EP claimed
US-20250115597-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF LYNK PHARMACEUTICALS CO LTD (CN) 2025-04-10 US disclosed
US-12129250-B2 TYK2 inhibitors and compositions and methods thereof LYNK PHARMACEUTICALS CO. LTD. (CN) 2024-10-29 US disclosed
US-20240124448-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF LYNK PHARMACEUTICALS CO. LTD. (CN) 2024-04-18 US disclosed
CN-114907514-A Multifunctional fiber and preparation method and application thereof 北京洁尔爽高科技有限公司 2022-08-16 CN disclosed
EP-2982368-A1 Small molecule compounds displacing focal adhesion core components Universität Konstanz (DE) 2016-02-10 EP disclosed
US-8946260-B2 17α-hydroxylase/C17,20-lyase inhibitors NOVARTIS AG (CH) 2015-02-03 US disclosed
US-20140045872-A1 17a-HYDROXYLASE/C17,20-LYASE INHIBITORS NOVARTIS AG (CH) 2014-02-13 US disclosed
EP-2627648-A1 17aHYDROXYLASE/C17,20-LYASE INHIBITORS Novartis AG (CH) 2013-08-21 EP disclosed
CN-103108871-A 17a-hydroxylase/c17,20-lyase inhibitors NOVARTIS AG 2013-05-15 CN disclosed
US-20110046142-A1 ANTIBIOTIC COMPOUNDS NORTHEASTERN UNIVERSITY (US) 2011-02-24 US disclosed
EP-2167074-A2 ANTIBIOTIC COMPOUNDS NorthEastern University (US) 2010-03-31 EP disclosed
WO-2008156610-A2 ANTIBIOTIC COMPOUNDS NORTHEASTERN UNIVERSITY (US) 2008-12-24 WO disclosed
WO-2008156610-A2 ANTIBIOTIC COMPOUNDS NORTHEASTERN UNIVERSITY (US) 2008-12-24 WO disclosed
EP-0833630-A4 NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE SUGEN INC (US) 1998-09-02 EP disclosed
US-5763470-A Benzopyran compounds and methods for their use SUGEN INC. (US) 1998-06-09 US disclosed
EP-0833630-A1 NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE Sugen, Inc. (US) 1998-04-08 EP disclosed
WO-1996040110-A1 NOVEL BENZOPYRAN COMPOUNDS AND METHODS FOR THEIR USE SUGEN, INC. (US) 1996-12-19 WO disclosed
US-5034381-A Antagonist CIBA-GEIGY CORPORATION (US) 1991-07-23 US disclosed
EP-0323807-A2 Certain 2-substituted adenosine derivatives CIBA-GEIGY AG (CH) 1989-07-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046142-A1 ANTIBIOTIC COMPOUNDS AADAC, SPOUT1, NRDC FBP1 588/4885VCP 3212/4885LMNA 2276/4885
US-20240124448-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF TYK2, JAK2, JAK1 FBP1 3141/4885VCP 3802/4885LMNA 974/4885
US-20250115597-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF TYK2, JAK2, JAK1 FBP1 3141/4885VCP 3802/4885LMNA 974/4885
US-12129250-B2 TYK2 inhibitors and compositions and methods thereof TYK2, JAK2, JAK1 FBP1 3141/4885VCP 3802/4885LMNA 974/4885
US-20140045872-A1 17a-HYDROXYLASE/C17,20-LYASE INHIBITORS CYP17A1, CYP21A2, HSD17B1 FBP1 2302/4885VCP 3835/4885LMNA 3690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.