Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8128846 | 0.91 | KDM4E (0.56) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| Fandofloxacin SCHEMBL1650067 | 0.88 | LMNA (0.74) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| Fandofloxacin SCHEMBL1230394 | 0.87 | LMNA (0.73) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL8133393 | 0.86 | KMT2A (0.54) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| Fandofloxacin SCHEMBL1650236 | 0.86 | LMNA (0.72) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL8123851 | 0.86 | KDM4E (0.47) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL8121818 | 0.86 | MEN1 (0.42) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL8122247 | 0.86 | KDM4E (0.47) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL8125009 | 0.85 | KMT2A (0.53) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL5195883 | 0.84 | KMT2A (0.58) | MEN1KMT2ALMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713487-B1 | NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES | DONG WHA PHARM IND CO LTD (KR) | 2000-04-19 | — | — | EP | disclosed |
| US-5496947-A | BACTERICIDES | DONG WHA PHARMACEUTICAL INDUSTRIAL CO., LTD. (KR) | 1996-03-05 | — | — | US | disclosed |
| WO-1995005373-A1 | NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES | DONG WHA PHARMACEUTICAL INDUSTRIAL CO., LTD. (KR) | 1995-02-23 | — | — | WO | disclosed |