Fandofloxacin

Fandofloxacin

SCHEMBL1650067

CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3-c2ccc(F)cn2)CC1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.74
▸ MEN1 O00255 2/20 0.74
▸ KMT2A Q03164 2/20 0.74
▸ ALDH1A1 P00352 7/20 0.61
▸ DRD3 P35462 1/20 0.61
▸ KDM4E B2RXH2 8/20 0.57
▸ HPGD P15428 4/20 0.57
▸ HSD17B10 Q99714 4/20 0.57
▸ NPC1 O15118 1/20 0.56
▸ GAA P10253 1/20 0.48
▸ RAD52 P43351 1/20 0.48
▸ MAPT P10636 1/20 0.48
▸ BRD4 O60885 1/20 0.48
▸ TSHR P16473 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ CYP2J2 P51589 1/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48
▸ PIK3CG P48736 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fandofloxacin SCHEMBL1230394 0.99 LMNA (0.73) LMNAMEN1KMT2AALDH1A1DRD3
Fandofloxacin SCHEMBL1650236 0.98 LMNA (0.72) LMNAMEN1KMT2AALDH1A1DRD3
SCHEMBL5195883 0.89 KMT2A (0.58) LMNAMEN1KMT2AALDH1A1DRD3
SCHEMBL8123703 0.89 LMNA (0.73) LMNAMEN1KMT2AALDH1A1DRD3
Hydrochloric Acid SCHEMBL8129182 0.88 LMNA (0.75) LMNAMEN1KMT2AALDH1A1DRD3
SCHEMBL8139807 0.88 MEN1 (0.57) LMNAMEN1KMT2AALDH1A1DRD3
SCHEMBL10666385 0.85 LMNA (0.81) LMNAMEN1KMT2AALDH1A1DRD3
Difloxacin SCHEMBL148765 0.85 LMNA (1.00) LMNAMEN1KMT2AALDH1A1DRD3
Difloxacin SCHEMBL29695838 0.85 LMNA (1.00) LMNAMEN1KMT2AALDH1A1DRD3
SCHEMBL8131272 0.84 LMNA (0.53) LMNAMEN1KMT2AALDH1A1DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023028364-A1 TARGETED COMPOSITIONS AND USES THEROF SEPELO THERAPEUTICS, LLC (US) 2023-03-02 — — WO claimed
US-20160045490-A1 USE OF CHEMOTHERAPEUTIC AGENTS BAYER INNOVATION GMBH (DE) 2016-02-18 — — US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 — — US claimed
US-20140287028-A1 Use of Chemotherapeutic Agents BAYER INNOVATION GMBH (DE) 2014-09-25 — — US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 — — US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 — — CN claimed
US-20070197501-A1 Use Of Chemotherapeutic Agents BAYER INNOVATION GMBH (DE) 2007-08-23 — — US claimed
EP-1408034-B1 Use of Quinolone and Quinolizinone derivatives as chemotherapeutic agents SCHULZ & SCHLIMBACH GBR (DE) 2007-08-08 — — EP claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 — — US claimed
CN-1668598-A Use of chemotherapeutic agents SCHULZ & SCHLIMBACH GBR (DE) 2005-09-14 — — CN claimed
EP-1408034-A1 Use of Quinoline derivatives as antibacterial agents Schulz & Schlimbach GbR (DE) 2004-04-14 — — EP claimed
US-20030045544-A1 Bactericides for the oral region of animals using 3-carboxy-4-oxo quinoline or 1,8-naphthyridine derivatives or 1-cyclopropyl-3-carboyx-4-oxo quinolizine derivatives BAYER INNOVATION GMBH (DE) 2003-03-06 — — US claimed
EP-1244434-A2 USE OF CHEMOTHERAPEUTIC AGENTS Schulz, Hans-Herrmann (DE) 2002-10-02 — — EP claimed
WO-2001045679-A2 USE OF CHEMOTHERAPEUTIC AGENTS FOR TOPICAL TREATMENT SCHULZ HANS HERRMANN (DE) 2001-06-28 — — WO claimed
EP-0713487-B1 NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES DONG WHA PHARM IND CO LTD (KR) 2000-04-19 — — EP claimed
JP-2758722-B2 — — 1998-05-28 — — JP claimed
US-5496947-A BACTERICIDES DONG WHA PHARMACEUTICAL INDUSTRIAL CO., LTD. (KR) 1996-03-05 — — US claimed
WO-1995005373-A1 NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES DONG WHA PHARMACEUTICAL INDUSTRIAL CO., LTD. (KR) 1995-02-23 — — WO claimed
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FIRST WAVE BIO, INC. 2024-03-07 — — US disclosed
WO-1995005373-A1 NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES DONG WHA PHARMACEUTICAL INDUSTRIAL CO., LTD. (KR) 1995-02-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FH, CS, ECHS1 LMNA 3221/4885MEN1 3463/4885KMT2A 3595/4885
US-20030045544-A1 Bactericides for the oral region of animals using 3-carboxy-4-oxo quinoline or 1,8-naphthyridine derivatives or 1-cyclopropyl-3-carboyx-4-oxo quinolizine derivatives NQO2, BROX, CYP4X1 LMNA 3991/4885MEN1 3548/4885KMT2A 4384/4885
US-20070197501-A1 Use Of Chemotherapeutic Agents TYMP, TP53, MSH2 LMNA 2610/4885MEN1 1055/4885KMT2A 4080/4885
US-20140287028-A1 Use of Chemotherapeutic Agents TYMP, TP53, MSH2 LMNA 2610/4885MEN1 1055/4885KMT2A 4080/4885
US-20160045490-A1 USE OF CHEMOTHERAPEUTIC AGENTS TYMP, TP53, MSH2 LMNA 2610/4885MEN1 1055/4885KMT2A 4080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback