Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140199 | 1.00 | RAB9A (0.59) | RAB9AHPGDNPC1KMT2AMEN1 | |
| SCHEMBL8994723 | 0.93 | ALDH1A1 (0.54) | RAB9AHPGDNPC1KMT2AMEN1 | |
| SCHEMBL8184701 | 0.89 | RAB9A (0.62) | RAB9AHPGDNPC1KMT2AMEN1 | |
| SCHEMBL8153001 | 0.89 | RAB9A (0.62) | RAB9AHPGDNPC1KMT2AMEN1 | |
| SCHEMBL8153005 | 0.89 | RAB9A (0.62) | RAB9AHPGDNPC1KMT2AMEN1 | |
| SCHEMBL25317423 | 0.84 | MAPT (0.53) | RAB9AHPGDNPC1KMT2AMEN1 | |
| SCHEMBL25321662 | 0.84 | ALDH1A1 (0.56) | RAB9AHPGDNPC1KMT2AMEN1 | |
| SCHEMBL9592865 | 0.84 | ALDH1A1 (0.45) | RAB9AHPGDNPC1KMT2AMEN1 | |
| SCHEMBL9592872 | 0.84 | ALDH1A1 (0.45) | RAB9AHPGDNPC1KMT2AMEN1 | |
| SCHEMBL376723 | 0.82 | ALDH1A1 (0.48) | HPGDKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150065-A | 1-(P-AMINOPHENYL)-1,4,4-TRIPHENYLBUTADIENE DERIVATIVE CHARGE TRANSFER COMPOUNDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0651024-B1 | Method of producing polymethine dyes | MINNESOTA MINING & MFG (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0651024-A1 | Method of producing polymethine dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-05-03 | — | — | EP | disclosed |
| US-5386058-A | Method of producing polymethine dyes | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-31 | — | — | US | disclosed |