SCHEMBL376723

SCHEMBL376723

O=CC=C(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
TDP1 Q9NUW8 4/20 0.48
MAPK1 P28482 2/20 0.48
CYP2C19 P33261 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
MCOLN3 Q8TDD5 1/20 0.45
CES1 P23141 3/20 0.43
CES2 O00748 2/20 0.43
TSHR P16473 2/20 0.43
DAO P14920 1/20 0.43
NAPRT Q6XQN6 1/20 0.43
AKT1 P31749 1/20 0.41
CA2 P00918 3/20 0.40
CYP3A4 P08684 2/20 0.40
MAPT P10636 2/20 0.40
CA4 P22748 2/20 0.40
CA12 O43570 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL8994735 0.91 ALDH1A1 (0.46) ALDH1A1TDP1MAPK1CYP2C19L3MBTL1
SCHEMBL29016164 0.87 CES2 (0.55) ALDH1A1L3MBTL1NPSR1CES1CES2
SCHEMBL18885235 0.87 CES2 (0.55) ALDH1A1TDP1CYP2C19L3MBTL1CYP1A2
SCHEMBL10579805 0.87 CES2 (0.55) ALDH1A1L3MBTL1NPSR1CES1CES2
SCHEMBL6776074 0.87 KMT2A (0.55) ALDH1A1TDP1MAPK1CYP2C19L3MBTL1
SCHEMBL1320539 0.87 CYP1B1 (0.44) ALDH1A1TDP1MAPK1CYP2C19CYP1A2
SCHEMBL20139669 0.87 CYP1B1 (0.44) ALDH1A1TDP1MAPK1CYP2C19CYP1A2
SCHEMBL6776075 0.87 KMT2A (0.55) ALDH1A1TDP1MAPK1CYP2C19L3MBTL1
SCHEMBL9472917 0.86 SMN1; SMN2 (0.48) TDP1MAPK1L3MBTL1CYP1A2CYP3A4
SCHEMBL9592865 0.84 ALDH1A1 (0.45) ALDH1A1TDP1MAPK1CYP2C19L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 514 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630758-B2 Downhole methods and compositions used in such DORF KETAL CHEMICALS FZE (AE) 2026-05-19 US claimed
US-12497557-B2 Methods for stimulating a hydrocarbon-bearing formation by perforating a wellbore and introducing an acidic composition in the wellbore DORF KETAL CHEMICALS FZE (AE) 2025-12-16 US claimed
CN-120117974-A Synthetic method for preparing di-deuterated primary alcohol by catalytic aldehyde hydrogenation and hydrogen-deuterium exchange reaction 中国科学院大连化学物理研究所 2025-06-10 CN claimed
US-12241021-B2 Method for fracking of simulation of hydrocarbon bearing formation DORF KETAL CHEMICALS FZE (AE) 2025-03-04 US claimed
US-20250011644-A1 NOVEL DOWNHOLE METHODS AND COMPOSITIONS USED IN SUCH DORF KETAL CHEMICALS FZE (AE) 2025-01-09 US claimed
US-20240301277-A1 Methods for Stimulating a Hydrocarbon-bearing Formation by Perforating a Wellbore and Introducing an Acidic Composition in the Wellbore DORF KETAL CHEMICALS FZE (AE) 2024-09-12 US claimed
US-20240279533-A1 DOWNHOLE METHODS AND COMPOSITIONS USED IN SUCH DORF KETAL CHEMICALS FZE (AE) 2024-08-22 US claimed
US-20240254383-A1 NOVEL DOWNHOLE METHODS AND COMPOSITIONS USED IN SUCH DORF KETAL CHEMICALS FZE (AE) 2024-08-01 US claimed
US-12018210-B2 Methods for stimulating a hydrocarbon-bearing formation by perforating a wellbore and introducing an acidic composition in the wellbore DORF KETAL CHEMICALS FZE (AE) 2024-06-25 US claimed
US-20240191128-A1 Methods for Stimulating a Hydrocarbon-bearing Formation by Perforating a Wellbore and Introducing an Acidic Composition in the Wellbore DORF KETAL CHEMICALS FZE (AE) 2024-06-13 US claimed
EP-1644312-A1 PREPARATION OF 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES Genfit (FR) 2006-04-12 EP claimed
WO-2005073184-A1 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVE COMPOUNDS, PREPARATION METHOD THEREOF AND USES OF SAME GENFIT (FR) 2005-08-11 WO claimed
WO-2005054544-A1 METHODS AND COMPOSITIONS FOR INHIBITING METAL CORROSION HALLIBURTON ENERGY SERVICES, INC. (US) 2005-06-16 WO claimed
US-20050123437-A1 Methods and compositions for inhibiting metal corrosion HALLIBURTON ENERGY SERVICES, INC. 2005-06-09 US claimed
EP-1525177-A1 SUBSTITUTED 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES AND PREPARATION AND USES THEREOF Genfit (FR) 2005-04-27 EP claimed
WO-2005005369-A1 PREPARATION OF 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES GENFIT (FR) 2005-01-20 WO claimed
US-20040132807-A1 Aurones as telomerase inhibitors PHARMACIA ITALIA SPA (IT) 2004-07-08 US claimed
EP-1381359-A1 AURONES AS TELOMERASE INHIBITORS Pharmacia Italia S.p.A. (IT) 2004-01-21 EP claimed
WO-2004005233-A1 SUBSTITUTED 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES AND PREPARATION AND USES THEREOF GENFIT (FR) 2004-01-15 WO claimed
WO-2002083123-A1 AURONES AS TELOMERASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2002-10-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630758-B2 Downhole methods and compositions used in such IL1B, GET3, IL17A ALDH1A1 4815/4885TDP1 4411/4885MAPK1 859/4885
US-20040132807-A1 Aurones as telomerase inhibitors TERT, TERF2, TERF2IP ALDH1A1 1344/4885TDP1 13/4885MAPK1 1740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.