Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21711093 | 0.81 | PDE10A (0.45) | PDE10AALOX5CASP1CA1CA2 | |
| SCHEMBL3969449 | 0.80 | ALOX5 (0.41) | PDE10AALOX5CASP1CA1CA2 | |
| SCHEMBL6941557 | 0.80 | MAOB (0.47) | CA1CA2GAASLC22A6SLC22A8 | |
| SCHEMBL3654298 | 0.80 | CASP1 (0.37) | ALOX5CASP1TSHRGAAALDH1A1 | |
| SCHEMBL3975247 | 0.80 | TDP1 (0.46) | PDE10AALOX5GAAALDH1A1KDM4E | |
| SCHEMBL2739345 | 0.79 | PDE10A (0.52) | PDE10AALOX5CASP1CA1CA2 | |
| SCHEMBL5681804 | 0.78 | PDE10A (0.50) | PDE10AALOX5CASP1CA1CA2 | |
| SCHEMBL3194749 | 0.78 | PDE10A (0.50) | PDE10AALOX5CASP1CA1CA2 | |
| SCHEMBL17774759 | 0.78 | PDE10A (0.50) | PDE10AALOX5CASP1CA1CA2 | |
| SCHEMBL17774755 | 0.78 | PDE10A (0.50) | PDE10AALOX5CASP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101374495-A | Colorant for keratin fibers | PROCTER & GAMBLE (US) | 2009-02-25 | — | — | CN | disclosed |
| US-6118008-A | FIBER-REACTIVE DYE; HAIR DYE | L'OREAL (FR) | 2000-09-12 | — | — | US | disclosed |