Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975247 | 0.92 | TDP1 (0.46) | ALOX5PDE10AALDH1A1GAATDP1 | |
| SCHEMBL3968067 | 0.90 | CYP3A4 (0.42) | ALOX5PDE10AALDH1A1HIF1ATDP1 | |
| SCHEMBL3968205 | 0.87 | ALOX5 (0.35) | ALOX5PDE10AALDH1A1GAAHTT | |
| SCHEMBL3970430 | 0.85 | PDE10A (0.42) | ALOX5PDE10AALDH1A1GAATDP1 | |
| SCHEMBL6535756 | 0.82 | TDP1 (0.39) | ALDH1A1GAATDP1TSHRCASP1 | |
| SCHEMBL3965393 | 0.80 | KDM4E (0.43) | ALOX5ALDH1A1GAATSHRCA1 | |
| SCHEMBL8140503 | 0.80 | PDE10A (0.45) | ALOX5PDE10AALDH1A1GAAHIF1A | |
| SCHEMBL3977541 | 0.79 | CHRNB4 (0.38) | ALOX5ALDH1A1HTTTDP1MEN1 | |
| SCHEMBL3968161 | 0.75 | PDE10A (0.39) | ALOX5PDE10ATSHRCASP1CA1 | |
| SCHEMBL2739345 | 0.75 | PDE10A (0.52) | ALOX5PDE10AALDH1A1GAAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359890-A4 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P & G CLAIROL INC (US) | 2009-08-12 | — | — | EP | disclosed |
| US-6673934-B2 | 4-AMINO-2-(1-ARYLOXY-ETHYL)PHENOL COMPOUND | THE PROCTER & GAMBLE COMPANY | 2004-01-06 | — | — | US | disclosed |
| EP-1359890-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-Clairol, Inc. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20020157192-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-31 | — | — | US | disclosed |
| WO-2002058631-A2 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-CLAIROL, INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020157192-A1 | Primary intermediates for oxidative coloration of hair | AOX1, CYC1, CBR1 | ALOX5 276/4885PDE10A 2017/4885ALDH1A1 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.