Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140724 | 0.90 | MTNR1A (0.45) | MTNR1AMTNR1BRXRANPC1MEN1 | |
| SCHEMBL8137983 | 0.84 | TSHR (0.53) | MTNR1AMTNR1BNPC1MEN1KMT2A | |
| SCHEMBL29265630 | 0.80 | NPC1 (0.49) | RXRANPC1MEN1KMT2APOLB | |
| SCHEMBL5710105 | 0.79 | ALOX5 (0.57) | RXRANPC1MEN1KMT2ARAB9A | |
| SCHEMBL20187701 | 0.78 | TSHR (0.48) | RXRANPC1MEN1KMT2APOLB | |
| SCHEMBL1221272 | 0.77 | TSHR (0.54) | RXRANPC1MEN1KMT2APOLB | |
| SCHEMBL4755619 | 0.77 | TSHR (0.54) | RXRANPC1MEN1KMT2APOLB | |
| SCHEMBL7774965 | 0.77 | HDAC1 (0.49) | MTNR1AMTNR1BMEN1KMT2APOLB | |
| SCHEMBL31003784 | 0.76 | KMO (0.45) | RXRAKMT2ASRD5A2 | |
| SCHEMBL652110 | 0.76 | KMT2A (0.45) | RXRANPC1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069149-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | TERUMO KABUSHIKI KAISHA (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0894797-A1 | NOVEL AMIDE DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | TERUMO KABUSHIKI KAISHA (JP) | 1999-02-03 | — | — | EP | disclosed |