Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28811325 | 0.93 | TAAR1 (0.47) | TAAR1IGF1RALOX15KCNH2HTR3E | |
| SCHEMBL1008937 | 0.93 | IGF1R (0.53) | TAAR1IGF1RALOX15KCNH2HTR3E | |
| SCHEMBL11460578 | 0.91 | KCNH2 (0.53) | TAAR1IGF1RALOX15KCNH2HTR3E | |
| SCHEMBL7562217 | 0.91 | KCNH2 (0.53) | TAAR1IGF1RALOX15KCNH2HTR3E | |
| SCHEMBL5596095 | 0.91 | KCNH2 (0.53) | TAAR1IGF1RALOX15KCNH2HTR3E | |
| SCHEMBL7217191 | 0.91 | KCNH2 (0.53) | TAAR1IGF1RALOX15KCNH2HTR3E | |
| SCHEMBL7464785 | 0.91 | KCNH2 (0.53) | TAAR1IGF1RALOX15KCNH2HTR3E | |
| SCHEMBL7562067 | 0.91 | KCNH2 (0.53) | TAAR1IGF1RALOX15KCNH2HTR3E | |
| SCHEMBL7614753 | 0.91 | KCNH2 (0.53) | TAAR1IGF1RALOX15KCNH2HTR3E | |
| SCHEMBL8071211 | 0.91 | KCNH2 (0.53) | TAAR1IGF1RALOX15KCNH2HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640104-B | Industrial synthesis method of telithromycin | 杭州科耀医药科技有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-116640104-A | Industrial synthesis method of telithromycin | 杭州科耀医药科技有限公司 | 2023-08-25 | — | — | CN | claimed |
| US-12564583-B2 | Small molecules against cereblon to enhance effector T cell function | Lee Moffitt Cancer Center and Research Institute, Inc. (US) | 2026-03-03 | — | — | US | disclosed |
| US-20250136581-A1 | SUBSTITUTED TRIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | SHANGHAI SIMRD BIOTECHNOLOGY CO., LTD. (CN) | 2025-05-01 | — | — | US | disclosed |
| CN-115703765-B | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| EP-4447963-A1 | SELECTIVE PHD1 INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Akebia Therapeutics Inc. (US) | 2024-10-23 | — | — | EP | disclosed |
| US-20240336568-A1 | SELECTIVE PHD1 INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | AKEBIA THERAPEUTICS, INC. (US) | 2024-10-10 | — | — | US | disclosed |
| CN-118715015-A | Selective PHD1 inhibitor compounds, compositions and methods of use | 阿克比治疗有限公司 | 2024-09-27 | — | — | CN | disclosed |
| EP-4385988-A1 | SUBSTITUTED TRIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | Shanghai Simr Biotechnology Co., Ltd. (CN) | 2024-06-19 | — | — | EP | disclosed |
| CN-116640104-B | Industrial synthesis method of telithromycin | 杭州科耀医药科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-116640104-B | Industrial synthesis method of telithromycin | 杭州科耀医药科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-0349062-A1 | Quinoline ether alkanoic acid | MERCK FROSST CANADA INC. (CA) | 1990-01-03 | — | — | EP | disclosed |
| EP-0347766-A2 | 4,5,7,8-Tetrahydro-6H-thiazolo[5,4-d]azepines, their preparation and their use as medicaments | Dr. Karl Thomae GmbH (DE) | 1989-12-27 | — | — | EP | disclosed |
| WO-1989004819-A1 | DERIVATIVES OF TRIFLUOROMETHYL-1-TETRALINES, PREPARATION AND APPLICATION THEREOF FOR THE SYNTHESIS OF COMPOUNDS HAVING THERAPEUTIC PROPERTIES | LABORATOIRES LUCIEN (FR) | 1989-06-01 | — | — | WO | disclosed |
| EP-0226636-B1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1989-02-08 | — | — | EP | disclosed |
| EP-0299684-A1 | Heterocyclic Compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-01-18 | — | — | EP | disclosed |
| EP-0250198-A2 | Bis-azolyl compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-12-23 | — | — | EP | disclosed |
| EP-0226636-A1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1987-07-01 | — | — | EP | disclosed |
| WO-1987000521-A2 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1987-01-29 | — | — | WO | disclosed |
| US-4222765-A | HERBICIDES FOR PADDY FIELDS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1980-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12564583-B2 | Small molecules against cereblon to enhance effector T cell function | CRBN, CD4, ICOS | TAAR1 1569/4885IGF1R 2393/4885ALOX15 1093/4885 |
| US-20250136581-A1 | SUBSTITUTED TRIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | GABRA5, SLC6A11, GABRA1 | TAAR1 1317/4885IGF1R 2444/4885ALOX15 808/4885 |
| US-20240336568-A1 | SELECTIVE PHD1 INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | HIF1AN, EGLN1, EGLN2 | TAAR1 3728/4885IGF1R 2149/4885ALOX15 817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.