Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81413 | 0.89 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL441050 | 0.89 | TSHR (0.60) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL16286807 | 0.88 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL16286690 | 0.88 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL19201572 | 0.84 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL15495149 | 0.84 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL3368716 | 0.83 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8965587 | 0.83 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL107386 | 0.81 | ALDH1A1 (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL17067685 | 0.81 | TSHR (0.58) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053528-B2 | Binder compositions for fiber mats, and fiber mats and articles comprising them | GEORGIA-PACIFIC CHEMICALS LLC (US) | 2011-11-08 | — | — | US | claimed |
| EP-2164902-A1 | BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM | Georgia-Pacific Chemicals LLC (US) | 2010-03-24 | — | — | EP | claimed |
| US-20090124151-A1 | BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM | GEORGIA-PACIFIC CHEMICALS LLC (US) | 2009-05-14 | — | — | US | claimed |
| WO-2008150647-A1 | BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM | GEORGIA-PACIFIC CHEMICALS, LLC (US) | 2008-12-11 | — | — | WO | claimed |
| US-12240868-B2 | Organic silicon compound and production method therefor | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-03-04 | — | — | US | disclosed |
| US-20240279441-A1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2024-08-22 | — | — | US | disclosed |
| US-20240279459-A1 | Curable Composition and Cured Product | SOKEN CHEMICAL & ENGINEERING CO., LTD. (JP) | 2024-08-22 | — | — | US | disclosed |
| EP-4353755-A1 | CURABLE COMPOSITION AND CURED PRODUCT | Soken Chemical & Engineering Co., Ltd. (JP) | 2024-04-17 | — | — | EP | disclosed |
| US-20240018358-A1 | POLYSILOXANE-BASED RESIN AND UTILIZATION THEREOF | KANEKA CORPORATION (JP) | 2024-01-18 | — | — | US | disclosed |
| EP-3783037-B1 | POLYMER HAVING REACTIVE SILICON-CONTAINING GROUP AND PRODUCTION METHOD THEREFOR | SHINETSU CHEMICAL CO (JP) | 2024-01-10 | — | — | EP | disclosed |
| CN-117377722-A | Rubber composition and tire | 株式会社普利司通 | 2024-01-09 | — | — | CN | disclosed |
| CN-117265895-A | Solvent-free environment-friendly low-viscosity high-performance printing silica gel and preparation method thereof | 广东聚思新材料科技有限公司 | 2023-12-22 | — | — | CN | disclosed |
| EP-2164902-A1 | BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM | Georgia-Pacific Chemicals LLC (US) | 2010-03-24 | — | — | EP | disclosed |
| US-20090249979-A1 | PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING ALPHA-SILANES AND METHOD FOR THE PRODUCTION THEREOF | ECKART GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090124151-A1 | BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM | GEORGIA-PACIFIC CHEMICALS LLC (US) | 2009-05-14 | — | — | US | disclosed |
| WO-2008150647-A1 | BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM | GEORGIA-PACIFIC CHEMICALS, LLC (US) | 2008-12-11 | — | — | WO | disclosed |
| US-20080242766-A1 | Curable Composition Containing Surface-Modified Particles | CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2008-10-02 | — | — | US | disclosed |
| EP-0486279-B2 | Process for removing acidic impurities from alkoxysilanes | SHINETSU CHEMICAL CO (JP) | 1999-12-01 | — | — | EP | disclosed |
| US-5247117-A | Neutralization with sterically hindered alcohols or amines, distillation | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0486279-A1 | Process for removing acidic impurities from alkoxysilanes | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12240868-B2 | Organic silicon compound and production method therefor | OR51E2, MSL1, SOS1 | TSHR 4456/4885HPGD 4522/4885ALDH1A1 2353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.