Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12615941 | 0.85 | ALDH1A1 (0.54) | TSHRLMNAALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL8533502 | 0.83 | TSHR (0.69) | TSHRLMNAALDH1A1KDM4ECYP2C19 | |
| SCHEMBL8843835 | 0.80 | ALDH1A1 (0.66) | LMNAALDH1A1HDAC3GAAHPGD | |
| SCHEMBL1073501 | 0.78 | CYP3A4 (0.51) | LMNAALDH1A1CYP2C19CYP3A4L3MBTL1 | |
| SCHEMBL8843319 | 0.77 | P2RX7 (0.54) | LMNAALDH1A1CYP2C19CYP3A4L3MBTL1 | |
| SCHEMBL8843236 | 0.77 | CYP3A4 (0.49) | LMNAALDH1A1CYP2C19CYP3A4L3MBTL1 | |
| SCHEMBL6698215 | 0.77 | GAA (0.61) | TSHRLMNACYP2C19CYP3A4L3MBTL1 | |
| SCHEMBL8843411 | 0.75 | ALDH1A1 (0.59) | LMNAALDH1A1KDM4EL3MBTL1HDAC3 | |
| SCHEMBL14781027 | 0.75 | MEN1 (0.77) | LMNAALDH1A1CYP2C19CYP3A4L3MBTL1 | |
| SCHEMBL8802684 | 0.75 | HDAC1 (0.63) | LMNAHDAC3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914574-A2 | NEW PROCESS | Cambrex Karlskoga Ab (SE) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014068333-A2 | NEW PROCESS | CAMBREX KARLSKOGA AB (SE) | 2014-05-08 | — | — | WO | disclosed |
| WO-2000000463-A1 | ANTICONVULSANT ENANTIOMERIC AMINO ACID DERIVATIVES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-01-06 | — | — | WO | disclosed |