Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17550886 | 0.90 | GAA (0.72) | TSHRRECQLGAAKMT2AMEN1 | |
| SCHEMBL2520897 | 0.89 | TSHR (0.63) | TSHRRECQLGAAKMT2AMEN1 | |
| SCHEMBL15912652 | 0.89 | TSHR (0.63) | TSHRRECQLGAAKMT2AMEN1 | |
| SCHEMBL8464732 | 0.87 | MEN1 (0.76) | TSHRRECQLGAAKMT2AMEN1 | |
| SCHEMBL14679424 | 0.85 | KMT2A (0.57) | GAAKMT2AMEN1CYP3A4CYP2C19 | |
| SCHEMBL8464921 | 0.84 | MEN1 (0.65) | TSHRRECQLGAAKMT2AMEN1 | |
| SCHEMBL24242176 | 0.83 | L3MBTL1 (0.59) | TSHRRECQLGAAKMT2AMEN1 | |
| SCHEMBL23135879 | 0.83 | HPGD (0.65) | GAAKMT2AMEN1CYP2C19ALDH1A1 | |
| SCHEMBL23135443 | 0.83 | LMNA (0.58) | TSHRGAALMNAALDH1A1HPGD | |
| SCHEMBL8142187 | 0.83 | TSHR (0.50) | TSHRRECQLGAACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3554490-A1 | PHARMACEUTICAL COMBINATION COMPRISING A T-TYPE CALCIUM CHANNEL BLOCKER | Idorsia Pharmaceuticals Ltd (CH) | 2019-10-23 | — | — | EP | claimed |
| CN-110072521-A | Pharmaceutical combination comprising a T-type calcium channel blocker | 爱杜西亚药品有限公司 | 2019-07-30 | — | — | CN | claimed |
| WO-2018109152-A1 | PHARMACEUTICAL COMBINATION COMPRISING A T-TYPE CALCIUM CHANNEL BLOCKER | IDORSIA PHARMACEUTICALS LTD (CH) | 2018-06-21 | — | — | WO | claimed |
| US-11274083-B2 | Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents | SYNGENTA CROP PROTECTION AG (CH) | 2022-03-15 | — | — | US | disclosed |
| EP-3728235-B1 | SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-09 | — | — | EP | disclosed |
| US-20210188904-A1 | METHOD FOR PRODUCING LACOSAMIDE AND INTERMEDIATE THEREOF | API CORPORATION (JP) | 2021-06-24 | — | — | US | disclosed |
| US-10975117-B2 | Method for producing lacosamide and intermediate thereof | API CORPORATION (JP) | 2021-04-13 | — | — | US | disclosed |
| US-20210087151-A1 | SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2021-03-25 | — | — | US | disclosed |
| EP-3659997-A1 | METHOD FOR PRODUCING LACOSAMIDE AND INTERMEDIATE THEREOF | API Corporation (JP) | 2020-06-03 | — | — | EP | disclosed |
| EP-3554490-A1 | PHARMACEUTICAL COMBINATION COMPRISING A T-TYPE CALCIUM CHANNEL BLOCKER | Idorsia Pharmaceuticals Ltd (CH) | 2019-10-23 | — | — | EP | disclosed |
| EP-2914574-B1 | NEW PROCESS | CAMBREX KARLSKOGA AB (SE) | 2019-10-02 | — | — | EP | disclosed |
| WO-2013072933-A2 | PROCESS FOR PREPARATION OF 2-ACETAMIDO-N-BENZYL-3-METHOXYPROPIONAMIDE | GLENMARK GENERICS LIMITED (IN) | 2013-05-23 | — | — | WO | disclosed |
| EP-2352721-B1 | NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB PHARMA GMBH (DE) | 2013-03-27 | — | — | EP | disclosed |
| WO-2013030654-A1 | PROCESSES FOR THE PREPARATION OF (R)-2-ACETAMIDO-N-BENZYL-3-METHOXYPROPIONAMIDE AND INTERMEDIATES THEREOF | SIGNA S.A. DE C.V. (MX) | 2013-03-07 | — | — | WO | disclosed |
| WO-2012069855-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | CAMBREX KARLSKOGA AB (SE) | 2012-05-31 | — | — | WO | disclosed |
| WO-2011130615-A2 | PREPARATION OF LACOSAMIDE | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011099033-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN LABORATORIES LIMITED (IN) | 2011-08-18 | — | — | WO | disclosed |
| WO-2010052011-A1 | NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB PHARMA, S.A. (BE) | 2010-05-14 | — | — | WO | disclosed |
| US-20080025940-A1 | Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof | L'OREAL (FR) | 2008-01-31 | — | — | US | disclosed |
| US-20080025940-A1 | Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof | L'OREAL (FR) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274083-B2 | Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents | UNG, TYMP, TYMS | TSHR 901/4885RECQL 1192/4885GAA 455/4885 |
| US-20210087151-A1 | SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | UNG, TYMP, TYMS | TSHR 901/4885RECQL 1192/4885GAA 455/4885 |
| US-20210188904-A1 | METHOD FOR PRODUCING LACOSAMIDE AND INTERMEDIATE THEREOF | CA3, TREH, NAAA | TSHR 3674/4885RECQL 4507/4885GAA 312/4885 |
| US-20080025940-A1 | Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof | KRT18, TYR, MC1R | TSHR 959/4885RECQL 4603/4885GAA 3721/4885 |
| US-10975117-B2 | Method for producing lacosamide and intermediate thereof | CA3, TREH, NAAA | TSHR 3674/4885RECQL 4507/4885GAA 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.