Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464525 | 1.00 | CTSK (0.48) | CTSKCTSSSIRT6SIRT1ITGB3 | |
| SCHEMBL9439085 | 0.90 | CTSK (0.58) | CTSKCTSS | |
| SCHEMBL464524 | 0.88 | CTSK (0.46) | CTSKCTSS | |
| SCHEMBL17265668 | 0.87 | CTSK (0.48) | CTSKCTSS | |
| SCHEMBL31549494 | 0.87 | CTSK (0.48) | CTSKCTSS | |
| SCHEMBL15743644 | 0.85 | CTSK (0.44) | CTSKCTSS | |
| SCHEMBL445007 | 0.85 | CTSK (0.44) | CTSKCTSSSIRT6SIRT1ITGB3 | |
| SCHEMBL9538440 | 0.85 | CTSK (0.54) | CTSKCTSS | |
| SCHEMBL15821190 | 0.85 | CTSK (0.46) | CTSKCTSSSIRT6SIRT1ITGB3 | |
| SCHEMBL7256814 | 0.84 | CCKBR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861228-B1 | LIPOPOLYAMINES AS TRANSFECTION AGENTS AND PHARMACEUTICAL USES THEREOF | AVENTIS PHARMA SA (FR) | 2000-08-23 | — | — | EP | disclosed |
| EP-0861228-A1 | LIPOPOLYAMINES AS TRANSFECTION AGENTS AND PHARMACEUTICAL USES THEREOF | Aventis Pharma S.A. (FR) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997018185-A1 | LIPOPOLYAMINES AS TRANSFECTION AGENTS AND PHARMACEUTICAL USES THEREOF | RHONE-POULENC RORER S.A. (FR) | 1997-05-22 | — | — | WO | disclosed |