Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770857 | 0.71 | ALDH1A1 (0.48) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4326438 | 0.70 | — | — | |
| SCHEMBL22995 | 0.70 | — | — | |
| SCHEMBL11285223 | 0.68 | ALDH1A1 (0.41) | MTNR1AMTNR1BALDH1A1NPSR1CYP1A2 | |
| SCHEMBL429187 | 0.68 | PTPN1 (0.48) | TDP1NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL283726 | 0.67 | CYP19A1 (0.42) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1411653 | 0.66 | — | — | |
| SCHEMBL1388477 | 0.65 | — | — | |
| SCHEMBL8122144 | 0.65 | — | — | |
| SCHEMBL28204262 | 0.65 | MAOA (0.41) | MTNR1AMTNR1BALDH1A1NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103920-A | Olefin polymerization process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-15 | — | — | US | claimed |
| US-5714556-A | USING CATALYST SYSTEM COMPRISING PRODUCT OF ZEROVALENT NICKEL COORDINATION COMPOUND, ACID, SELECTED COMPOUND | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1998-02-03 | — | — | US | claimed |
| WO-1997002298-A1 | OLEFIN POLYMERIZATION PROCESS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-23 | — | — | WO | claimed |