Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL616625 | 0.79 | CYP19A1 (0.39) | CYP19A1CYP11B2TDP1PTGS2ESR1 | |
| SCHEMBL8820541 | 0.76 | ALDH1A1 (0.46) | TDP1ESR1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL482817 | 0.74 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| SCHEMBL16288649 | 0.74 | — | — | |
| SCHEMBL8063620 | 0.70 | — | — | |
| SCHEMBL11076088 | 0.69 | MAPT (0.56) | CYP19A1TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL11076083 | 0.69 | MAPT (0.56) | CYP19A1TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL7761248 | 0.69 | KMT2A (0.45) | CYP19A1TDP1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5664436 | 0.69 | — | — | |
| SCHEMBL339221 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2943584-B1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | CANON KK (JP) | 2019-08-14 | — | — | EP | disclosed |
| CN-108570004-A | A kind of compound that there is double action to 5-HT and its application in treating depression | 郝惠敏 | 2018-09-25 | — | — | CN | disclosed |
| CN-108484485-A | A kind of compound that there is double action to 5-HT and its application in treating depression | 郝惠敏 | 2018-09-04 | — | — | CN | disclosed |
| CN-108484544-A | A kind of compound that there is double action to 5-HT and its application in treating depression | 郝惠敏 | 2018-09-04 | — | — | CN | disclosed |
| US-10041937-B2 | Macrophage identification agent, and identification method, sorting method, evaluation method, screening method and kit using the macrophage identifier agent | CANON KABUSHIKI KAISHA (JP) | 2018-08-07 | — | — | US | disclosed |
| US-9801960-B2 | Probe for a biological specimen and labelling method and screening method using the probe | CANON KABUSHIKI KAISHA (JP) | 2017-10-31 | — | — | US | disclosed |
| US-9764046-B2 | Labeling composition for intraocular tissue, labeling method of intraocular tissue, and screening method | CANON KABUSHIKI KAISHA (JP) | 2017-09-19 | — | — | US | disclosed |
| EP-2370110-B1 | LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD | CANON KK (JP) | 2017-08-02 | — | — | EP | disclosed |
| EP-2204194-B1 | Probe for a hair cell, and labelling method for a hair cell using the probe for a hair cell | CANON KK (JP) | 2017-08-02 | — | — | EP | disclosed |
| US-20160018389-A1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | CANON KABUSHIKI KAISHA (JP) | 2016-01-21 | — | — | US | disclosed |
| US-8460639-B2 | Probe for a hair cell, and labelling method for a hair cell using the probe for a hair cell | CANON KABUSHIKI KAISHA (JP) | 2013-06-11 | — | — | US | disclosed |
| EP-2428230-A1 | Probe for auditory hair cells. | Canon Kabushiki Kaisha (JP) | 2012-03-14 | — | — | EP | disclosed |
| US-20110243850-A1 | PROBE FOR A BIOLOGICAL SPECIMEN AND LABELLING METHOD AND SCREENING METHOD USING THE PROBE | CANON KABUSHIKI KAISHA (JP) | 2011-10-06 | — | — | US | disclosed |
| EP-2370111-A1 | PROBE FOR A BIOLOGICAL SPECIMEN AND LABELLING METHOD AND SCREENING METHOD USING THE PROBE | Canon Kabushiki Kaisha (JP) | 2011-10-05 | — | — | EP | disclosed |
| EP-2370110-A1 | LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD | Canon Kabushiki Kaisha (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-20110236310-A1 | LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD | CANON KABUSHIKI KAISHA (JP) | 2011-09-29 | — | — | US | disclosed |
| EP-2204194-A2 | Probe for a hair cell, and labelling method for a hair cell using the probe for a hair cell | Canon Kabushiki Kaisha (JP) | 2010-07-07 | — | — | EP | disclosed |
| US-20100166663-A1 | PROBE FOR A HAIR CELL, AND LABELLING METHOD FOR A HAIR CELL USING THE PROBE FOR A HAIR CELL | CANON KABUSHIKI KAISHA (JP) | 2010-07-01 | — | — | US | disclosed |
| WO-2010074326-A1 | PROBE FOR A BIOLOGICAL SPECIMEN AND LABELLING METHOD AND SCREENING METHOD USING THE PROBE | CANON KABUSHIKI KAISHA (JP) | 2010-07-01 | — | — | WO | disclosed |
| WO-2010074325-A1 | LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD | CANON KABUSHIKI KAISHA (JP) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110236310-A1 | LABELING COMPOSITION FOR INTRAOCULAR TISSUE, LABELING METHOD OF INTRAOCULAR TISSUE, AND SCREENING METHOD | ALDH1A2, PDE6C, CHAT | CYP19A1 2062/4885CYP11B2 2037/4885TDP1 2825/4885 |
| US-10041937-B2 | Macrophage identification agent, and identification method, sorting method, evaluation method, screening method and kit using the macrophage identifier agent | CD68, MSR1, MYADM | CYP19A1 2729/4885CYP11B2 3903/4885TDP1 4751/4885 |
| US-20110243850-A1 | PROBE FOR A BIOLOGICAL SPECIMEN AND LABELLING METHOD AND SCREENING METHOD USING THE PROBE | FUCA1, FABP2, ALPI | CYP19A1 555/4885CYP11B2 511/4885TDP1 2647/4885 |
| US-20160018389-A1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | CD68, MSR1, MYADM | CYP19A1 2729/4885CYP11B2 3903/4885TDP1 4751/4885 |
| US-20100166663-A1 | PROBE FOR A HAIR CELL, AND LABELLING METHOD FOR A HAIR CELL USING THE PROBE FOR A HAIR CELL | ALPG, MKI67, KRT18 | CYP19A1 1729/4885CYP11B2 602/4885TDP1 2384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.