Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8142197 | 1.00 | NFKB1 (0.31) | NFKB1NFKB2RELA | |
| SCHEMBL8141733 | 0.90 | NFKB1 (0.30) | NFKB1NFKB2RELA | |
| SCHEMBL8151645 | 0.90 | NFKB1 (0.30) | NFKB1NFKB2RELA | |
| SCHEMBL221457 | 0.73 | — | — | |
| SCHEMBL8149726 | 0.69 | BTK (0.44) | NFKB1NFKB2RELA | |
| SCHEMBL7735878 | 0.69 | BTK (0.44) | NFKB1NFKB2RELA | |
| SCHEMBL7488055 | 0.68 | CYP4F2 (0.30) | — | |
| SCHEMBL10669809 | 0.65 | — | — | |
| SCHEMBL28476403 | 0.65 | — | — | |
| SCHEMBL10519878 | 0.65 | ARG1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000001714-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-01-13 | — | — | WO | disclosed |