Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.57 |
| ▸ | DAO | P14920 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2970468 | 0.84 | PGR (0.78) | PGRDAOPOLBFEN1MAOB | |
| SCHEMBL29464129 | 0.84 | PGR (0.78) | PGRDAOPOLBFEN1MAOB | |
| SCHEMBL9598853 | 0.81 | PGR (0.53) | PGRDAOPOLBMAOB | |
| SCHEMBL30770202 | 0.79 | GRIA1 (0.56) | PGRDAOKDM4EOPRM1OPRL1 | |
| SCHEMBL8346146 | 0.78 | PGR (0.40) | PGRDAOKDM4EOPRM1OPRL1 | |
| SCHEMBL7282502 | 0.77 | POLB (0.69) | DAOKDM4EOPRM1OPRL1POLB | |
| SCHEMBL31236070 | 0.77 | POLB (0.69) | DAOKDM4EOPRM1OPRL1POLB | |
| SCHEMBL28836860 | 0.77 | PGR (0.67) | PGRDAOPOLBFEN1MAOB | |
| SCHEMBL8145145 | 0.76 | DAO (0.70) | DAOKDM4EOPRM1OPRL1FEN1 | |
| SCHEMBL8346149 | 0.75 | PGR (0.37) | PGRDAOKDM4EOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993012113-A1 | 3-SUBSTITUTED IMIDAZO (1,5-a) AND IMIDAZO (1,5-a)-TRIAZOLO (1,5-c) QUINOXALINES AND QUINAZOLINES WITH CNS ACTIVITY | THE UPJOHN COMPANY (US) | 1993-06-24 | — | — | WO | disclosed |