Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18393466 | 1.00 | NAMPT (0.33) | NAMPTTDP1GSK3BKCNH2 | |
| SCHEMBL8145696 | 1.00 | NAMPT (0.33) | NAMPTTDP1GSK3BKCNH2 | |
| SCHEMBL2194777 | 0.85 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| SCHEMBL14768401 | 0.82 | NAMPT (0.33) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL7762050 | 0.80 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL182310 | 0.80 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| SCHEMBL8016496 | 0.80 | NAMPT (0.32) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL28442208 | 0.80 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL26337 | 0.80 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| SCHEMBL8016500 | 0.80 | NAMPT (0.32) | NAMPTGSK3BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103758-A | APPLYING TO A TICK, A HOST ANIMAL OF TICKS IN NEED OF TREATMENT AN EFFECTIVE AMOUNT OF A 1-(TETRA HYDROFURAN)METHYL-2-NITROGUANIDINE MITICIDE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2000-08-15 | — | — | US | claimed |