Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18393466 | 1.00 | NAMPT (0.33) | NAMPTTDP1GSK3BKCNH2 | |
| SCHEMBL8145694 | 1.00 | NAMPT (0.33) | NAMPTTDP1GSK3BKCNH2 | |
| SCHEMBL2194777 | 0.85 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| SCHEMBL14768401 | 0.82 | NAMPT (0.33) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL7762050 | 0.80 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL182310 | 0.80 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| SCHEMBL8016496 | 0.80 | NAMPT (0.32) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL28442208 | 0.80 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| Dinotefuran SCHEMBL26337 | 0.80 | NAMPT (0.34) | NAMPTGSK3BKCNH2 | |
| SCHEMBL8016500 | 0.80 | NAMPT (0.32) | NAMPTGSK3BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103758-A | APPLYING TO A TICK, A HOST ANIMAL OF TICKS IN NEED OF TREATMENT AN EFFECTIVE AMOUNT OF A 1-(TETRA HYDROFURAN)METHYL-2-NITROGUANIDINE MITICIDE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2000-08-15 | — | — | US | claimed |
| EP-3324955-B1 | COMPOSITION COMPRISING FIPRONIL AND DINOTEFURAN FOR USE IN AMETHOD OF CONTROLLING FLEAS IN NON HUMAN MAMMALS | CEVA SANTE ANIMALE (FR) | 2026-04-29 | — | — | EP | disclosed |
| US-11134685-B2 | Compositions and uses thereof for controlling ectoparasites in non-human mammals | Ceva Santé Animale (FR) | 2021-10-05 | — | — | US | disclosed |
| EP-3358953-B1 | VETERINARY COMPOSITIONS FOR THE CONTROL OF PHLEBOTOMES | CEVA SANTE ANIMALE (FR) | 2021-05-19 | — | — | EP | disclosed |
| US-10952988-B2 | Methods for controlling the spread of dirofilariosis | Ceva Santé Animale (FR) | 2021-03-23 | — | — | US | disclosed |
| US-20200163339-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | Ceva Santé Animale (FR) | 2020-05-28 | — | — | US | disclosed |
| US-20180279620-A1 | VETERINARY COMPOSITIONS FOR SANDFLY CONTROL | CEVA SANTE ANIMALE (FR) | 2018-10-04 | — | — | US | disclosed |
| US-20180235926-A1 | METHODS FOR CONTROLLING THE SPREAD OF DIROFILARIOSIS | Ceva Santè Animale (FR) | 2018-08-23 | — | — | US | disclosed |
| US-20180213790-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | Ceva Santé Animale (FR) | 2018-08-02 | — | — | US | disclosed |
| EP-3259990-A1 | METHODS FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | Ceva Sante Animale (FR) | 2017-12-27 | — | — | EP | disclosed |
| EP-3183968-A1 | METHODS AND MEANS FOR THE ERADICATION OF FLEAS | Ceva Sante Animale (FR) | 2017-06-28 | — | — | EP | disclosed |
| EP-3120846-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | Ceva Sante Animale (FR) | 2017-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11134685-B2 | Compositions and uses thereof for controlling ectoparasites in non-human mammals | NISCH, NAMPT, TYR | NAMPT 2/4885TDP1 2681/4885GSK3B 4650/4885 |
| US-20180235926-A1 | METHODS FOR CONTROLLING THE SPREAD OF DIROFILARIOSIS | NISCH, DDT, TNNT2 | NAMPT 75/4885TDP1 3744/4885GSK3B 4224/4885 |
| US-10952988-B2 | Methods for controlling the spread of dirofilariosis | NISCH, DDT, TNNT2 | NAMPT 75/4885TDP1 3744/4885GSK3B 4224/4885 |
| US-20180279620-A1 | VETERINARY COMPOSITIONS FOR SANDFLY CONTROL | NISCH, SGMS1, SGMS2 | NAMPT 72/4885TDP1 3501/4885GSK3B 4799/4885 |
| US-20180213790-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | NISCH, NAMPT, TYR | NAMPT 2/4885TDP1 2681/4885GSK3B 4650/4885 |
| US-20200163339-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | NISCH, NAMPT, TYR | NAMPT 2/4885TDP1 2681/4885GSK3B 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.