Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802147 | 0.93 | KMT2A (0.49) | LMNAALDH1A1HPGDNPSR1TSHR | |
| SCHEMBL6803985 | 0.92 | KMT2A (0.48) | LMNAALDH1A1HPGDNPSR1KDM4E | |
| SCHEMBL6806695 | 0.91 | LMNA (0.53) | LMNAALDH1A1HPGDNPSR1KDM4E | |
| SCHEMBL6803657 | 0.83 | DRD3 (0.53) | LMNAALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL6798944 | 0.82 | GAA (0.51) | LMNAALDH1A1HPGDNPSR1KDM4E | |
| SCHEMBL6801698 | 0.81 | ALDH1A1 (0.42) | LMNAALDH1A1HPGDTSHRKMT2A | |
| SCHEMBL6802393 | 0.78 | TOP1 (0.39) | LMNAALDH1A1HPGDKDM4ETSHR | |
| SCHEMBL6795945 | 0.77 | MAPT (0.45) | LMNATSHRKMT2AMEN1GAA | |
| SCHEMBL6806653 | 0.76 | TOP1 (0.51) | LMNAGAATHRBTP53RXFP1 | |
| SCHEMBL6798609 | 0.76 | SRC (0.41) | ALDH1A1HPGDKDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028950-A1 | NOVEL 7-SUBSTITUTED QUINAZOLIN-2,4-DIONES USEFUL AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999021840-A1 | NOVEL 7-SUBSTITUTED QUINAZOLIN-2,4-DIONES USEFUL AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-05-06 | — | — | WO | disclosed |