Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | HTT | P42858 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GALR3 | O60755 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2514962 | 0.98 | TLR8 (0.47) | TLR8NPC1RAB9AHTTPOLB | |
| SCHEMBL22504083 | 0.96 | TLR8 (0.43) | TLR8NPC1RAB9AHTTPOLB | |
| SCHEMBL19303315 | 0.94 | TLR8 (0.42) | TLR8NPC1RAB9AHTTPOLB | |
| SCHEMBL12122681 | 0.90 | LPO (0.46) | TLR8NPC1RAB9AHTTPOLB | |
| SCHEMBL12122682 | 0.90 | LPO (0.46) | TLR8NPC1RAB9AHTTPOLB | |
| SCHEMBL972632 | 0.90 | LPO (0.46) | TLR8NPC1RAB9AHTTPOLB | |
| SCHEMBL587358 | 0.80 | LPO (0.50) | TLR8NPC1RAB9APOLBLMNA | |
| SCHEMBL5670030 | 0.74 | LPO (0.44) | — | |
| SCHEMBL6678530 | 0.74 | PTGS1 (0.48) | TLR8NPC1RAB9AHTTPOLB | |
| SCHEMBL11612693 | 0.74 | EEF2K (0.44) | TLR8NPC1RAB9AHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025496-A | Process for preparing heterocyclic carbenes | CELANESE GMBH (DE) | 2000-02-15 | — | — | US | disclosed |