Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPO | P22079 | 3/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | GALR3 | O60755 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12122682 | 1.00 | LPO (0.46) | LPOTLR8NPC1RAB9AHTT | |
| SCHEMBL12122681 | 1.00 | LPO (0.46) | LPOTLR8NPC1RAB9AHTT | |
| SCHEMBL587358 | 0.92 | LPO (0.50) | LPOTLR8NPC1RAB9ALMNA | |
| SCHEMBL8146236 | 0.90 | TLR8 (0.46) | TLR8NPC1RAB9AHTTLMNA | |
| SCHEMBL2514962 | 0.87 | TLR8 (0.47) | LPOTLR8NPC1RAB9AHTT | |
| SCHEMBL22504083 | 0.86 | TLR8 (0.43) | TLR8NPC1RAB9AHTTLMNA | |
| SCHEMBL19303315 | 0.84 | TLR8 (0.42) | LPOTLR8NPC1RAB9AHTT | |
| SCHEMBL972118 | 0.83 | LPO (0.55) | LPOLMNASMN1; SMN2PTGS1CYP1A2 | |
| SCHEMBL587606 | 0.76 | — | — | |
| SCHEMBL10723024 | 0.76 | PTGS1 (0.47) | TLR8NPC1RAB9AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411927-B1 | Coating compositions containing 1,3-dialkylimidazole-2-thione catalysts | DU PONT (US) | 1995-01-18 | — | — | EP | claimed |
| US-5162482-A | 1,3-dialkylimidazole-2-thione catalysts and method of making same | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-10 | — | — | US | claimed |
| US-5091498-A | Alkali resistant coatings | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-02-25 | — | — | US | claimed |
| EP-0411927-A1 | Coating compositions containing 1,3-dialkylimidazole-2-thione catalysts | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-02-06 | — | — | EP | claimed |
| US-8057780-B2 | Method for preparing nanoparticles using carbene derivatives | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-11-15 | — | — | US | disclosed |
| US-8057780-B2 | Method for preparing nanoparticles using carbene derivatives | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-11-15 | — | — | US | disclosed |
| US-7868182-B2 | Solventless one-step process for the production of imidazole-2-thiones | ARDUENGO III ANTHONY J | 2011-01-11 | — | — | US | disclosed |
| US-20090289233-A1 | METHOD FOR PREPARING NANOPARTICLES USING CARBENE DERIVATIVES | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-11-26 | — | — | US | disclosed |
| US-20090289233-A1 | METHOD FOR PREPARING NANOPARTICLES USING CARBENE DERIVATIVES | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-11-26 | — | — | US | disclosed |
| US-20080171883-A1 | Solventless One-Step Process for the Production of Imidazole-2-thiones | ARDUENGO ANTHONY J | 2008-07-17 | — | — | US | disclosed |
| EP-0411927-B1 | Coating compositions containing 1,3-dialkylimidazole-2-thione catalysts | DU PONT (US) | 1995-01-18 | — | — | EP | disclosed |
| US-5162482-A | 1,3-dialkylimidazole-2-thione catalysts and method of making same | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| US-5104993-A | Reacting 1-alkylimidazole and alkyl halide; contacting product with a suspension of sulfur and an alkali metal alkoxide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| US-5091498-A | Alkali resistant coatings | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0411927-A1 | Coating compositions containing 1,3-dialkylimidazole-2-thione catalysts | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171883-A1 | Solventless One-Step Process for the Production of Imidazole-2-thiones | TST, TPMT, CYP2E1 | LPO 1809/4885TLR8 2852/4885NPC1 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.