Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPO | P22079 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12122682 | 0.92 | LPO (0.46) | LPOKMT2AALDH1A1POLBLMNA | |
| SCHEMBL972632 | 0.92 | LPO (0.46) | LPOKMT2AALDH1A1POLBLMNA | |
| SCHEMBL12122681 | 0.92 | LPO (0.46) | LPOKMT2AALDH1A1POLBLMNA | |
| SCHEMBL972118 | 0.86 | LPO (0.55) | LPOKMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL2514962 | 0.82 | TLR8 (0.47) | LPOKMT2AALDH1A1POLBLMNA | |
| SCHEMBL8146236 | 0.80 | TLR8 (0.46) | KMT2AALDH1A1POLBLMNACYP1A2 | |
| SCHEMBL587606 | 0.79 | — | — | |
| SCHEMBL22504083 | 0.77 | TLR8 (0.43) | KMT2AALDH1A1POLBLMNACYP1A2 | |
| SCHEMBL19303315 | 0.75 | TLR8 (0.42) | LPOKMT2AALDH1A1POLBLMNA | |
| SCHEMBL24885966 | 0.74 | ALDH1A1 (0.42) | KMT2AALDH1A1POLBLMNATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411927-B1 | Coating compositions containing 1,3-dialkylimidazole-2-thione catalysts | DU PONT (US) | 1995-01-18 | — | — | EP | claimed |
| US-5091498-A | Alkali resistant coatings | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-02-25 | — | — | US | claimed |
| EP-0411927-A1 | Coating compositions containing 1,3-dialkylimidazole-2-thione catalysts | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-02-06 | — | — | EP | claimed |
| JP-3137118-A | — | — | None | — | — | JP | disclosed |
| US-9751841-B2 | Process for the preparation of chalcogene compounds | PETROLIAM NASIONAL BERHAD (MY) | 2017-09-05 | — | — | US | disclosed |
| EP-2417109-B1 | PROCESS FOR THE PREPARATION OF CHALCOGENE COMPOUNDS | PETROLIAM NASIONAL BERHAD PETRONAS (MY) | 2014-12-03 | — | — | EP | disclosed |
| US-20120108822-A1 | Process For The Preparation Of Chalcogene Compounds | PETROLIAM NASIONAL BERHAD (MY) | 2012-05-03 | — | — | US | disclosed |
| EP-2417109-A2 | PROCESS FOR THE PREPARATION OF CHALCOGENE COMPOUNDS | Petroliam Nasional Berhad (MY) | 2012-02-15 | — | — | EP | disclosed |
| US-8057780-B2 | Method for preparing nanoparticles using carbene derivatives | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-11-15 | — | — | US | disclosed |
| US-8057780-B2 | Method for preparing nanoparticles using carbene derivatives | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-11-15 | — | — | US | disclosed |
| US-7868182-B2 | Solventless one-step process for the production of imidazole-2-thiones | ARDUENGO III ANTHONY J | 2011-01-11 | — | — | US | disclosed |
| US-5189160-A | For preparing high molecular weight aramids by ring opening polymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| WO-1992019665-A1 | CYCLIC AROMATIC AMIDE OLIGOMERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5162482-A | 1,3-dialkylimidazole-2-thione catalysts and method of making same | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| US-5104993-A | Reacting 1-alkylimidazole and alkyl halide; contacting product with a suspension of sulfur and an alkali metal alkoxide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| US-5091498-A | Alkali resistant coatings | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-02-25 | — | — | US | disclosed |
| US-5084542-A | Clear colorless resistant coatings with improved weatherability | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| WO-1991018937-A1 | EPOXY/ISOCYANATE CROSSLINKED COATINGS CONTAINING 1,3-DISUBSTITUTED IMIDAZOLE-2-THIONE CATALYSTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-12 | — | — | WO | disclosed |
| JP-H03137118-A | COATING COMPOSITION CONTAINING 1,3-DIALKYLIMIDAZOL-2-THIONE CATALYST | E I DU PONT DE NEMOURS & CO | 1991-06-11 | — | — | JP | disclosed |
| EP-0411927-A1 | Coating compositions containing 1,3-dialkylimidazole-2-thione catalysts | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108822-A1 | Process For The Preparation Of Chalcogene Compounds | SCO2, NISCH, AQP1 | LPO 2135/4885KMT2A 2912/4885ALDH1A1 4011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.