Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28735227 | 0.83 | NPC1 (0.49) | ADRB2ADRB1ADRB3TSHRNPC1 | |
| SCHEMBL777261 | 0.78 | NPC1 (0.53) | ADRB2ADRB1ADRB3TSHRNPC1 | |
| SCHEMBL29436920 | 0.78 | NPC1 (0.53) | ADRB2ADRB1ADRB3TSHRNPC1 | |
| SCHEMBL9831155 | 0.78 | NPC1 (0.46) | ADRB2ADRB1ADRB3TSHRNPC1 | |
| SCHEMBL8948919 | 0.78 | TSHR (0.52) | ADRB2ADRB1ADRB3TSHRNPC1 | |
| SCHEMBL2654989 | 0.77 | TSHR (0.47) | ADRB2ADRB1ADRB3TSHRNPC1 | |
| SCHEMBL10004127 | 0.75 | NPC1 (0.50) | ADRB2ADRB1ADRB3TSHRNPC1 | |
| SCHEMBL29201681 | 0.75 | NPC1 (0.50) | ADRB2ADRB1ADRB3TSHRNPC1 | |
| SCHEMBL27501656 | 0.75 | TSHR (0.58) | ADRB2ADRB1ADRB3TSHRNPC1 | |
| SCHEMBL22773852 | 0.74 | ADRB2 (0.45) | ADRB2ADRB1ADRB3TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049682-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | Versicor, Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037630-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | VERSICOR, INC. (US) | 1999-07-29 | — | — | WO | disclosed |