Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.62 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12046788 | 0.83 | DRD2 (0.54) | DRD2HRH3 | |
| SCHEMBL8152790 | 0.83 | MEN1 (0.53) | DRD2 | |
| SCHEMBL3440015 | 0.82 | DRD2 (0.61) | DRD2DRD4 | |
| SCHEMBL27458577 | 0.82 | HTR2A (0.51) | DRD2DRD4 | |
| SCHEMBL8549810 | 0.82 | TRPV1 (0.53) | DRD2DRD4 | |
| SCHEMBL10118660 | 0.80 | DRD2 (0.51) | DRD2HRH3 | |
| Hydrochloric Acid SCHEMBL27908881 | 0.80 | DRD2 (0.72) | DRD2 | |
| SCHEMBL8543870 | 0.79 | ITGB3 (0.53) | DRD2DRD4 | |
| SCHEMBL5987374 | 0.79 | HTR2A (0.59) | DRD2DRD4HRH3 | |
| SCHEMBL8147637 | 0.78 | MCHR1 (0.49) | DRD2DRD4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119741-A2 | 3-IMIDAZOLYL-INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2008-10-09 | — | — | WO | disclosed |