Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP8 | P40818 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8147770 | 1.00 | MAOA (0.53) | MAOAMAOBELANELCKCA1 | |
| SCHEMBL9353826 | 0.83 | MAOA (0.68) | MAOAMAOBELANELCKCA1 | |
| SCHEMBL8459324 | 0.80 | APAF1 (0.60) | MAOAELANEBCL2MCL1ALDH1A1 | |
| SCHEMBL23271984 | 0.78 | MAOA (0.73) | MAOAMAOBELANELCKCA1 | |
| SCHEMBL30003553 | 0.78 | MAOA (0.73) | MAOAMAOBELANELCKCA1 | |
| SCHEMBL3691403 | 0.75 | PTPN1 (0.47) | MAOAMAOBELANELCKCA1 | |
| SCHEMBL3699283 | 0.75 | PTPN1 (0.47) | MAOAMAOBELANELCKCA1 | |
| SCHEMBL182959 | 0.74 | ELANE (0.86) | MAOAMAOBELANELCKCA1 | |
| SCHEMBL583153 | 0.74 | ELANE (0.86) | MAOAMAOBELANELCKCA1 | |
| SCHEMBL10424226 | 0.73 | NPC1 (0.72) | MAOAMAOBELANELCKCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162799-A | Pesticidal compounds | BTG INTERNATIONAL LIMITED (GB) | 2000-12-19 | — | — | US | disclosed |
| US-5962002-A | 1,1,4,4-SUBSTITUTED DIHYDRONAPHTHALENE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1999-10-05 | — | — | US | disclosed |
| EP-0802730-B1 | PESTICIDAL COMPOUNDS | BTG INT LTD (GB) | 1999-06-23 | — | — | EP | disclosed |
| WO-1997002271-A1 | PESTICIDAL COMPOUNDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-01-23 | — | — | WO | disclosed |
| WO-1996021355-A1 | PESTICIDAL COMPOUNDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-07-18 | — | — | WO | disclosed |