Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 2/20 | 0.60 |
| ▸ | TDP2 | O95551 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16932387 | 0.81 | APAF1 (0.52) | APAF1TDP2ALDH1A1RAB9ANPC1 | |
| SCHEMBL8405065 | 0.81 | APAF1 (0.52) | APAF1TDP2ALDH1A1RAB9ANPC1 | |
| SCHEMBL4784189 | 0.80 | APAF1 (0.50) | APAF1TDP2ALDH1A1RAB9ANPC1 | |
| SCHEMBL8147176 | 0.80 | MAOA (0.53) | APAF1TDP2ALDH1A1RAB9ANPC1 | |
| SCHEMBL14305201 | 0.80 | MAOA (0.60) | ALDH1A1MEN1KMT2ACDC25BMAPT | |
| SCHEMBL8147770 | 0.80 | MAOA (0.53) | APAF1TDP2ALDH1A1RAB9ANPC1 | |
| SCHEMBL1102013 | 0.77 | CDC25B (0.52) | APAF1TDP2ALDH1A1RAB9ANPC1 | |
| SCHEMBL461648 | 0.77 | APAF1 (1.00) | APAF1TDP2ALDH1A1RAB9ANPC1 | |
| SCHEMBL29678361 | 0.77 | APAF1 (1.00) | APAF1TDP2ALDH1A1RAB9ANPC1 | |
| SCHEMBL9321186 | 0.77 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AMAPTMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962002-A | 1,1,4,4-SUBSTITUTED DIHYDRONAPHTHALENE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1999-10-05 | — | — | US | disclosed |
| EP-0802730-B1 | PESTICIDAL COMPOUNDS | BTG INT LTD (GB) | 1999-06-23 | — | — | EP | disclosed |
| EP-0802730-A1 | PESTICIDAL COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021355-A1 | PESTICIDAL COMPOUNDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-07-18 | — | — | WO | disclosed |