Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8150968 | 0.89 | BLM (0.40) | PNMTSLC6A2 | |
| SCHEMBL8147837 | 0.84 | PNMT (0.38) | PNMTHTR2AGAASLC6A2SLC6A3 | |
| SCHEMBL22328059 | 0.77 | GAA (0.53) | GAA | |
| Fumaric Acid SCHEMBL8153286 | 0.75 | BLM (0.43) | PNMTHTR2ASLC6A2 | |
| SCHEMBL905771 | 0.71 | HTR2A (0.55) | PNMTHTR2ASLC6A2SLC6A3 | |
| SCHEMBL8147219 | 0.70 | HTR2A (0.40) | HTR2AHTR2C | |
| SCHEMBL27051467 | 0.67 | — | — | |
| SCHEMBL6748800 | 0.66 | HTR2C (0.62) | HTR2AHTR2C | |
| SCHEMBL30166149 | 0.66 | SLC6A2 (0.50) | HTR2AGAASLC6A2SLC6A3HTR2C | |
| SCHEMBL5989957 | 0.66 | SLC6A2 (0.50) | HTR2AGAASLC6A2SLC6A3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000012482-A2 | INDAZOLE DERIVATIVES WITH 5-HT2 RECEPTOR ACTIVITY | VERNALIS RESEARCH LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |