Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.62 |
| ▸ | HTR2B | P41595 | 8/20 | 0.62 |
| ▸ | HTR2A | P28223 | 8/20 | 0.62 |
| ▸ | HTR1A | P08908 | 6/20 | 0.62 |
| ▸ | HTR1D | P28221 | 5/20 | 0.62 |
| ▸ | HTR6 | P50406 | 2/20 | 0.62 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | HTR1B | P28222 | 1/20 | 0.62 |
| ▸ | HTR7 | P34969 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6751698 | 0.99 | HTR2C (0.61) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL6205030 | 0.78 | HTR2C (0.50) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL5784125 | 0.78 | HTR2C (0.38) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL5784122 | 0.78 | HTR2C (0.38) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL5781742 | 0.78 | HTR2C (0.38) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL6202353 | 0.77 | HTR2C (0.49) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL5936562 | 0.77 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL6092065 | 0.77 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL30390274 | 0.77 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR1AHTR1D | |
| SCHEMBL6094978 | 0.77 | HTR2C (1.00) | HTR2CHTR2BHTR2AHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696476-B2 | SUCH AS 1-(2-AMINOPROPYL)-1,7,8,9-TETRAHYDRO-PYRANO(2,3-G)-INDAZOL-8-OL; LOWERING AND CONTROLLING INTRAOCULAR PRESSURE | ALCON, INC. (CH) | 2004-02-24 | — | — | US | claimed |
| US-20030171418-A1 | Reducing or controlling eye pressure | NOVARTIS AG (CH) | 2003-09-11 | — | — | US | claimed |
| US-6696476-B2 | SUCH AS 1-(2-AMINOPROPYL)-1,7,8,9-TETRAHYDRO-PYRANO(2,3-G)-INDAZOL-8-OL; LOWERING AND CONTROLLING INTRAOCULAR PRESSURE | ALCON, INC. (CH) | 2004-02-24 | — | — | US | disclosed |
| US-20030171418-A1 | Reducing or controlling eye pressure | NOVARTIS AG (CH) | 2003-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171418-A1 | Reducing or controlling eye pressure | PDE3A, PDE3B, QDPR | HTR2C 1978/4885HTR2B 1919/4885HTR2A 1849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.